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-Structure paper
Title | Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4) |
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Journal, issue, pages | Elife, Year 2024 |
Publish date | Aug 15, 2023 (structure data deposition date) |
Authors | Ravala SK / Adame-Garcia SR / Li S / Chen C / Cianfrocco MA / Gutkind JS / Cash JN / Tesmer JJG |
External links | Elife / Search PubMed |
Methods | EM (single particle) |
Resolution | 4.1 Å |
Structure data | EMDB-41621, PDB-8tua: |
Chemicals | ChemComp-4IP: |
Source |
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Keywords | SIGNALING PROTEIN / Rho guanine-nucleotide exchange factor / Dbl homology domain / pleckstrin homology domain / Phosphatidylinositol 3 / 4 / 5-trisphosphate binding |