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-Structure paper
Title | Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling. |
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Journal, issue, pages | Biochemistry, Vol. 62, Page 3206-3213, Year 2023 |
Publish date | Dec 23, 2022 (structure data deposition date) |
Authors | Brenner, R.J. / Landgraf, A.D. / Bum-Erdene, K. / Gonzalez-Gutierrez, G. / Meroueh, S.O. |
External links | Biochemistry / PubMed:37938120 |
Methods | X-ray diffraction |
Resolution | 1.12 - 1.48 Å |
Structure data | PDB-8fmi: PDB-8fmj: PDB-8fmk: |
Chemicals | ChemComp-MG: ChemComp-GDP: ChemComp-HOH: ChemComp-GOL: ChemComp-TRS: ChemComp-PEG: ChemComp-CL: |
Source |
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Keywords | HYDROLASE / cancer |