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-Structure paper
Title | A small-molecule PI3K alpha activator for cardioprotection and neuroregeneration. |
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Journal, issue, pages | Nature, Vol. 618, Page 159-168, Year 2023 |
Publish date | Aug 13, 2021 (structure data deposition date) |
![]() | Gong, G.Q. / Bilanges, B. / Allsop, B. / Masson, G.R. / Roberton, V. / Askwith, T. / Oxenford, S. / Madsen, R.R. / Conduit, S.E. / Bellini, D. ...Gong, G.Q. / Bilanges, B. / Allsop, B. / Masson, G.R. / Roberton, V. / Askwith, T. / Oxenford, S. / Madsen, R.R. / Conduit, S.E. / Bellini, D. / Fitzek, M. / Collier, M. / Najam, O. / He, Z. / Wahab, B. / McLaughlin, S.H. / Chan, A.W.E. / Feierberg, I. / Madin, A. / Morelli, D. / Bhamra, A. / Vinciauskaite, V. / Anderson, K.E. / Surinova, S. / Pinotsis, N. / Lopez-Guadamillas, E. / Wilcox, M. / Hooper, A. / Patel, C. / Whitehead, M.A. / Bunney, T.D. / Stephens, L.R. / Hawkins, P.T. / Katan, M. / Yellon, D.M. / Davidson, S.M. / Smith, D.M. / Phillips, J.B. / Angell, R. / Williams, R.L. / Vanhaesebroeck, B. |
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Methods | X-ray diffraction |
Resolution | 2.20029074868 - 2.57 Å |
Structure data | ![]() PDB-7pg5: ![]() PDB-7pg6: ![]() PDB-8bfu: ![]() PDB-8ow2: |
Chemicals | ![]() ChemComp-PO4: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-1LT: ![]() ChemComp-NA: ![]() ChemComp-QIH: |
Source |
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