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-Structure paper
Title | Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons. |
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Journal, issue, pages | Open Biology, Vol. 12, Page 220187-220187, Year 2022 |
Publish date | Nov 1, 2021 (structure data deposition date) |
Authors | Widagdo, J. / Udagedara, S. / Bhembre, N. / Tan, J.Z.A. / Neureiter, L. / Huang, J. / Anggono, V. / Lee, M. |
External links | Open Biology / PubMed:36168806 |
Methods | X-ray diffraction |
Resolution | 1.83 Å |
Structure data | PDB-7sp0: |
Chemicals | ChemComp-ZN: ChemComp-HOH: |
Source |
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Keywords | RNA BINDING PROTEIN / SFPQ / DBHS PROTEIN / RRM / ZN / POLYMERIZATION / NUCLEAR PROTEIN / ALS mutation |