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-Structure paper
Title | Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. |
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Journal, issue, pages | Elife, Vol. 10, Year 2021 |
Publish date | Nov 2, 2020 (structure data deposition date) |
Authors | Chen, X. / Ali, Y.I. / Fisher, C.E. / Arribas-Bosacoma, R. / Rajasekaran, M.B. / Williams, G. / Walker, S. / Booth, J.R. / Hudson, J.J. / Roe, S.M. ...Chen, X. / Ali, Y.I. / Fisher, C.E. / Arribas-Bosacoma, R. / Rajasekaran, M.B. / Williams, G. / Walker, S. / Booth, J.R. / Hudson, J.J. / Roe, S.M. / Pearl, L.H. / Ward, S.E. / Pearl, F.M. / Oliver, A.W. |
External links | Elife / PubMed:33647232 |
Methods | X-ray diffraction |
Resolution | 1.53 - 2.96 Å |
Structure data | PDB-7auc: PDB-7aud: |
Chemicals | ChemComp-ACT: ChemComp-EDO: ChemComp-PG4: ChemComp-GOL: ChemComp-ADP: ChemComp-MG: ChemComp-ZN: ChemComp-CA: ChemComp-HOH: ChemComp-RY8: |
Source |
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Keywords | NUCLEAR PROTEIN / Helicase / RecQ / BLM / DNA Repair / Inhibitor / Allosteric |