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-Structure paper
Title | Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015. |
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Journal, issue, pages | J. Biol. Chem., Vol. 295, Page 5404-5418, Year 2020 |
Publish date | Oct 10, 2019 (structure data deposition date) |
Authors | Dagbay, K.B. / Treece, E. / Streich Jr., F.C. / Jackson, J.W. / Faucette, R.R. / Nikiforov, A. / Lin, S.C. / Boston, C.J. / Nicholls, S.B. / Capili, A.D. / Carven, G.J. |
External links | J. Biol. Chem. / PubMed:32075906 |
Methods | X-ray diffraction |
Resolution | 2.79 Å |
Structure data | PDB-6umx: |
Chemicals | ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN/IMMUNE SYSTEM / Myostatin / GDF8 / transforming growth factor beta / muscle wasting disease / antibody / fab / SIGNALING PROTEIN-IMMUNE SYSTEM complex |