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-Structure paper
Title | p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. |
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Journal, issue, pages | Science, Vol. 366, Year 2019 |
Publish date | Jun 7, 2019 (structure data deposition date) |
![]() | Guiley, K.Z. / Stevenson, J.W. / Lou, K. / Barkovich, K.J. / Kumarasamy, V. / Wijeratne, T.U. / Bunch, K.L. / Tripathi, S. / Knudsen, E.S. / Witkiewicz, A.K. ...Guiley, K.Z. / Stevenson, J.W. / Lou, K. / Barkovich, K.J. / Kumarasamy, V. / Wijeratne, T.U. / Bunch, K.L. / Tripathi, S. / Knudsen, E.S. / Witkiewicz, A.K. / Shokat, K.M. / Rubin, S.M. |
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Methods | X-ray diffraction |
Resolution | 2.3 - 3.19 Å |
Structure data | ![]() PDB-6p8e: ![]() PDB-6p8f: ![]() PDB-6p8g: ![]() PDB-6p8h: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-HOH: |
Source |
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