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-Structure paper
Title | A study of the reactivity of S(VI)-F containing warheads with nucleophilic amino-acid side chains under physiological conditions. |
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Journal, issue, pages | Org. Biomol. Chem., Vol. 15, Page 9685-9695, Year 2017 |
Publish date | May 26, 2017 (structure data deposition date) |
Authors | Mukherjee, H. / Debreczeni, J. / Breed, J. / Tentarelli, S. / Aquila, B. / Dowling, J.E. / Whitty, A. / Grimster, N.P. |
External links | Org. Biomol. Chem. / PubMed:29119993 |
Methods | X-ray diffraction |
Resolution | 1.91 - 2.01 Å |
Structure data | PDB-5o49: PDB-5o4a: |
Chemicals | ChemComp-9K5: ChemComp-SO4: ChemComp-HOH: ChemComp-GOL: ChemComp-9K8: |
Source |
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Keywords | TRANSFERASE / FGFR Fibroblast Growth Factor / covalent inhibition / FGFR Fibroblast Grwth Fctr RTK |