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Structure paper

TitleAvian-to-Human Receptor-Binding Adaptation by Influenza A Virus Hemagglutinin H4
Journal, issue, pagesCell Rep, Vol. 20, Page 1201-1214, Year 2017
Publish dateMay 10, 2017 (structure data deposition date)
AuthorsSong, H. / Qi, J. / Xiao, H. / Bi, Y. / Zhang, W. / Xu, Y. / Wang, F. / Shi, Y. / Gao, G.F.
External linksCell Rep / PubMed:28768203
MethodsX-ray diffraction
Resolution2.001 - 2.5 Å
Structure data

PDB-5xl1:
The structure of hemagglutinin from an avian-origin H4N6 influenza virus
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5xl2:
The structure of hemagglutininfrom a swine-origin H4N6 influenza virus
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5xl3:
Complex structure of H4 hemagglutinin from avian influenza H4N6 virus with LSTa
Method: X-RAY DIFFRACTION / Resolution: 2.203 Å

PDB-5xl4:
The structure of hemagglutinin from an avian-origin H4N6 influenza virus in complex with human receptor analog Lstc
Method: X-RAY DIFFRACTION / Resolution: 2.102 Å

PDB-5xl5:
The structure of hemagglutinin Q226L mutant from an avian-origin H4N6 influenza virus
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-5xl6:
The structure of hemagglutinin Q226L mutant from a avian-origin H4N6 influenza virus
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

PDB-5xl7:
The structure of hemagglutinin Q226L mutant from an avian-origin H4N6 influenza virus in complex with human receptor analog LSTc
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5xl8:
The structure of hemagglutinin G228S mutant from a avian-origin H4N6 influenza virus (A/duck/Czech/1956)
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

PDB-5xl9:
The structure of hemagglutinin G228S mutant from an avian-origin H4N6 influenza virus in complex with avian receptor analog LSTa
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

PDB-5xla:
The structure of hemagglutinin G228S mutant from an avian-origin H4N6 influenza virus in complex with human receptor analog LSTc
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5xlb:
The structure of hemagglutinin Q226L-G228S mutant from an avian-origin H4N6 influenza virus
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-5xlc:
The structure of hemagglutinin Q226L-G228S mutant from an avian-origin H4N6 influenza virus in complex with avian receptor analog LSTa
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-5xld:
The structure of hemagglutinin Q226L-G228S mutant from an avian-origin H4N6 influenza virus in complex with human receptor analog LSTc
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose / N-Acetylglucosamine

ChemComp-HOH:
WATER / Water

ChemComp-SIA:
N-acetyl-alpha-neuraminic acid / Sialic acid

Source
  • influenza a virus (strain a/duck/czechoslovakia/1956 h4n6)
  • influenza a virus (a/swine/ontario/01911-1/99 (h4n6))
  • influenza a virus
KeywordsVIRAL PROTEIN / H4 hemagglutinin / influenza virus / receptor binding

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