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TitleControllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting.
Journal, issue, pagesAdv Mater, Vol. 28, Issue 34, Page 7501-7507, Year 2016
Publish dateJun 20, 2016
AuthorsHui Li / Kaiming Zhang / Fengmei Pi / Sijin Guo / Luda Shlyakhtenko / Wah Chiu / Dan Shu / Peixuan Guo /
PubMed AbstractRNA tetrahedral nanoparticles with two different sizes are successfully assembled by a one-pot bottom-up approach with high efficiency and thermal stability. The reported design principles can be ...RNA tetrahedral nanoparticles with two different sizes are successfully assembled by a one-pot bottom-up approach with high efficiency and thermal stability. The reported design principles can be extended to construct higher-order polyhedral RNA architectures for various applications such as targeted cancer imaging and therapy.
External linksAdv Mater / PubMed:27322097 / PubMed Central
MethodsEM (single particle)
Resolution19.0 - 23.0 Å
Structure data

EMDB-8233:
8 nm RNA Tetrahedron
Method: EM (single particle) / Resolution: 19.0 Å

EMDB-8234:
17 nm RNA Tetrahedron
Method: EM (single particle) / Resolution: 23.0 Å

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