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-Structure paper
Title | A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening. |
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Journal, issue, pages | J Biomol Screen, Vol. 20, Page 810-820, Year 2015 |
Publish date | Dec 19, 2014 (structure data deposition date) |
Authors | Wigle, T.J. / Swinger, K.K. / Campbell, J.E. / Scholle, M.D. / Sherrill, J. / Admirand, E.A. / Boriack-Sjodin, P.A. / Kuntz, K.W. / Chesworth, R. / Moyer, M.P. ...Wigle, T.J. / Swinger, K.K. / Campbell, J.E. / Scholle, M.D. / Sherrill, J. / Admirand, E.A. / Boriack-Sjodin, P.A. / Kuntz, K.W. / Chesworth, R. / Moyer, M.P. / Scott, M.P. / Copeland, R.A. |
External links | J Biomol Screen / PubMed:25755264 |
Methods | X-ray diffraction |
Resolution | 1.97 - 2.07 Å |
Structure data | PDB-4xdo: PDB-4xdp: |
Chemicals | ChemComp-ZN: ChemComp-FE: ChemComp-OGA: ChemComp-PGE: ChemComp-EDO: ChemComp-PG4: ChemComp-HOH: ChemComp-TRS: ChemComp-CL: |
Source |
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Keywords | OXIDOREDUCTASE / LYSINE-SPECIFIC DEMETHYLASE 4C |