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-Structure paper
Title | Exploring novel strategies for AIDS protozoal pathogens: alpha-helix mimetics targeting a key allosteric protein-protein interaction in C. hominis TS-DHFR. |
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Journal, issue, pages | Medchemcomm, Vol. 4, Page 1247-1256, Year 2013 |
Publish date | May 20, 2009 (structure data deposition date) |
Authors | Martucci, W.E. / Rodriguez, J.M. / Vargo, M.A. / Marr, M. / Hamilton, A.D. / Anderson, K.S. |
External links | Medchemcomm / PubMed:24324854 |
Methods | X-ray diffraction |
Resolution | 2.7 Å |
Structure data | PDB-3hj3: |
Chemicals | ChemComp-UMP: ChemComp-CB3: ChemComp-MTX: ChemComp-NDP: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / TS / DHFR / ENZYME / CROSSOVER / NON-ACTIVE SITE |