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-Structure paper
Title | Combined X-ray, NMR, and kinetic analyses reveal uncommon binding characteristics of the hepatitis C virus NS3-NS4A protease inhibitor BI 201335. |
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Journal, issue, pages | J. Biol. Chem., Vol. 286, Page 11434-11443, Year 2011 |
Publish date | Oct 14, 2010 (structure data deposition date) |
Authors | Lemke, C.T. / Goudreau, N. / Zhao, S. / Hucke, O. / Thibeault, D. / Llinas-Brunet, M. / White, P.W. |
External links | J. Biol. Chem. / PubMed:21270126 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.3 Å |
Structure data | PDB-3p8n: PDB-3p8o: |
Chemicals | ChemComp-NA: ChemComp-L4T: ChemComp-HOH: ChemComp-L5T: |
Source |
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Keywords | HYDROLASE/HYDROLASE inhibitor / Hepatitis C Virus / NS3 / NS4A / halogen bond / serine protease / HYDROLASE-HYDROLASE inhibitor complex |