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-Structure paper
Title | Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors |
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Journal, issue, pages | Plos One, Vol. 5, Page e15535-e15535, Year 2010 |
Publish date | Jun 18, 2010 (structure data deposition date) |
![]() | King, O.N.F. / Li, X.S. / Sakurai, M. / Kawamura, A. / Rose, N.R. / Ng, S.S. / Quinn, A.M. / Rai, G. / Mott, B.T. / Beswick, P. ...King, O.N.F. / Li, X.S. / Sakurai, M. / Kawamura, A. / Rose, N.R. / Ng, S.S. / Quinn, A.M. / Rai, G. / Mott, B.T. / Beswick, P. / Klose, R.J. / Oppermann, U. / Jadhav, A. / Heightman, T.D. / Maloney, D.J. / Schofield, C.J. / Simeonov, A. |
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Methods | X-ray diffraction |
Resolution | 2.6 Å |
Structure data | ![]() PDB-3njy: |
Chemicals | ![]() ChemComp-NI: ![]() ChemComp-ZN: ![]() ChemComp-8XQ: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / ![]() ![]() |