+Search query
-Structure paper
Title | Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 18, Page 4237-4241, Year 2008 |
Publish date | May 12, 2008 (structure data deposition date) |
Authors | Hamblin, J.N. / Angell, T.D. / Ballantine, S.P. / Cook, C.M. / Cooper, A.W. / Dawson, J. / Delves, C.J. / Jones, P.S. / Lindvall, M. / Lucas, F.S. ...Hamblin, J.N. / Angell, T.D. / Ballantine, S.P. / Cook, C.M. / Cooper, A.W. / Dawson, J. / Delves, C.J. / Jones, P.S. / Lindvall, M. / Lucas, F.S. / Mitchell, C.J. / Neu, M.Y. / Ranshaw, L.E. / Solanke, Y.E. / Somers, D.O. / Wiseman, J.O. |
External links | Bioorg. Med. Chem. Lett. / PubMed:18539455 |
Methods | X-ray diffraction |
Resolution | 1.75 Å |
Structure data | PDB-3d3p: |
Chemicals | ChemComp-ZN: ChemComp-MG: ChemComp-20A: ChemComp-ARS: ChemComp-HOH: |
Source |
|
Keywords | HYDROLASE / PDE / PHOSPHODIESTERASE / cAMP / Alternative splicing / Phosphoprotein / Polymorphism |