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-Structure paper
Title | Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 1, Page 525-533, Year 2006 |
Publish date | Aug 18, 2006 (structure data deposition date) |
![]() | Zobel, K. / Wang, L. / Varfolomeev, E. / Franklin, M.C. / Elliott, L.O. / Wallweber, H.J. / Okawa, D.C. / Flygare, J.A. / Vucic, D. / Fairbrother, W.J. / Deshayes, K. |
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Methods | X-ray diffraction |
Resolution | 1.62 - 2.3 Å |
Structure data | ![]() PDB-2i3h: ![]() PDB-2i3i: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-LI: ![]() ChemComp-BTB: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-618: |
Source |
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![]() | INHIBITOR/APOPTOSIS / ![]() ![]() ![]() ![]() ![]() |