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-Structure paper
Title | An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors. |
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Journal, issue, pages | J. Mol. Biol., Vol. 361, Page 673-686, Year 2006 |
Publish date | May 31, 2006 (structure data deposition date) |
Authors | Yin, J. / Cherney, M.M. / Bergmann, E.M. / Zhang, J. / Huitema, C. / Pettersson, H. / Eltis, L.D. / Vederas, J.C. / James, M.N. |
External links | J. Mol. Biol. / PubMed:16860823 |
Methods | X-ray diffraction |
Resolution | 1.35 - 1.4 Å |
Structure data | PDB-2h6m: PDB-2h9h: PDB-2hal: |
Chemicals | ChemComp-BBL: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / BETA BARREL / HYDROLASE-HYDROLASE INHIBITOR COMPLEX / METHYLKETONE / EPISULFIDE / HYDROLASE-HYDRLASE INHIBITOR COMPLEX / HEPATITIS A VIRUS / 3C PROTEASE / INHIBITOR DESIGN / PICORNAIN |