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-Structure paper
Title | Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design |
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Journal, issue, pages | Protein Sci., Vol. 15, Page 949-960, Year 2006 |
Publish date | Sep 19, 2005 (structure data deposition date) |
Authors | Clark, L.A. / Boriack-Sjodin, P.A. / Eldredge, J. / Fitch, C. / Friedman, B. / Hanf, K.J. / Jarpe, M. / Liparoto, S.F. / Li, Y. / Lugovskoy, A. ...Clark, L.A. / Boriack-Sjodin, P.A. / Eldredge, J. / Fitch, C. / Friedman, B. / Hanf, K.J. / Jarpe, M. / Liparoto, S.F. / Li, Y. / Lugovskoy, A. / Miller, S. / Rushe, M. / Sherman, W. / Simon, K. / Van Vlijmen, H. |
External links | Protein Sci. / PubMed:16597831 |
Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | PDB-2b2x: |
Chemicals | ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / computational design / antibody-antigen complex |