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-Structure paper
Title | Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors. |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 61, Page 1418-1425, Year 2005 |
Publish date | Apr 26, 2005 (structure data deposition date) |
Authors | Jin, L. / Pandey, P. / Babine, R.E. / Weaver, D.T. / Abdel-Meguid, S.S. / Strickler, J.E. |
External links | Acta Crystallogr. ,Sect. D / PubMed:16204896 |
Methods | X-ray diffraction |
Resolution | 1.73 - 2.7 Å |
Structure data | PDB-1zhm: PDB-1zhp: PDB-1zhr: |
Chemicals | ChemComp-BEN: ChemComp-GSH: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / BLOOD CLOTTING / Factor XI; benzamidine |