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-Structure paper
Title | X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease. |
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Journal, issue, pages | J. Biol. Chem., Vol. 280, Page 23815-23819, Year 2005 |
Publish date | Dec 10, 2004 (structure data deposition date) |
Authors | Premkumar, L. / Sawkar, A.R. / Boldin-Adamsky, S. / Toker, L. / Silman, I. / Kelly, J.W. / Futerman, A.H. / Sussman, J.L. |
External links | J. Biol. Chem. / PubMed:15817452 |
Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | PDB-1y7v: |
Chemicals | ChemComp-SO4: ChemComp-INS: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / GAUCHER DISEASE / GLUCOSIDASE / GLUCOCEREBROSIDASE / CEREZYME / GLYCOSIDASE / SPHINGOLIPID METABOLISM / GLYCOPROTEIN / LYSOSOME / MEMBRANE / DISEASE MUTATION / ALTERNATIVE INITIATION / Israel Structural Proteomics Center / ISPC / Structural Genomics |