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Title | Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 14, Page 3581-3584, Year 2004 |
Publish date | Jul 8, 2003 (structure data deposition date) |
![]() | Sawyer, J.S. / Beight, D.W. / Britt, K.S. / Anderson, B.D. / Campbell, R.M. / Goodson, T. / Herron, D.K. / Li, H.Y. / McMillen, W.T. / Mort, N. ...Sawyer, J.S. / Beight, D.W. / Britt, K.S. / Anderson, B.D. / Campbell, R.M. / Goodson, T. / Herron, D.K. / Li, H.Y. / McMillen, W.T. / Mort, N. / Parsons, S. / Smith, E.C. / Wagner, J.R. / Yan, L. / Zhang, F. / Yingling, J.M. |
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Methods | X-ray diffraction |
Resolution | 2.3 - 2.4 Å |
Structure data | ![]() PDB-1py5: ![]() PDB-1rw8: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-PY1: ![]() ChemComp-HOH: ![]() ChemComp-580: |
Source |
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