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Title | Structural Insights into the Human and Avian IMP Cyclohydrolase Mechanism via Crystal Structures with the Bound XMP Inhibitor. |
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Journal, issue, pages | Biochemistry, Vol. 43, Page 1171-1183, Year 2004 |
Publish date | Jun 6, 2003 (structure data deposition date) |
Authors | Wolan, D.W. / Cheong, C.G. / Greasley, S.E. / Wilson, I.A. |
External links | Biochemistry / PubMed:14756553 |
Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | PDB-1pkx: |
Chemicals | ChemComp-K: ChemComp-XMP: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / HYDROLASE / ATIC / AICAR transformylase / IMP Cyclohydrolase / xanthosine monophosphate / purine biosynthesis |