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-Structure paper
Title | Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data. |
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Journal, issue, pages | J. Biol. Chem., Vol. 278, Page 20851-20859, Year 2003 |
Publish date | Apr 21, 2003 (structure data deposition date) |
Authors | Kuo, M.R. / Morbidoni, H.R. / Alland, D. / Sneddon, S.F. / Gourlie, B.B. / Staveski, M.M. / Leonard, M. / Gregory, J.S. / Janjigian, A.D. / Yee, C. ...Kuo, M.R. / Morbidoni, H.R. / Alland, D. / Sneddon, S.F. / Gourlie, B.B. / Staveski, M.M. / Leonard, M. / Gregory, J.S. / Janjigian, A.D. / Yee, C. / Musser, J.M. / Kreiswirth, B. / Iwamoto, H. / Perozzo, R. / Jacobs, W.R. / Sacchettini, J.C. / Fidock, D.A. |
External links | J. Biol. Chem. / PubMed:12606558 |
Methods | X-ray diffraction |
Resolution | 2.6 - 2.7 Å |
Structure data | PDB-1p44: PDB-1p45: |
Chemicals | ChemComp-NAD: ChemComp-GEQ: ChemComp-HOH: ChemComp-TCL: |
Source |
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Keywords | OXIDOREDUCTASE / InhA / short chain dehydrogenase reductase / inhibitor / rossmann fold / enoyl-ACP reductase / Structural Genomics / PSI / Protein Structure Initiative / TB Structural Genomics Consortium / TBSGC / triclosan |