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-Structure paper
Title | Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL. |
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Journal, issue, pages | Nature, Vol. 417, Page 975-978, Year 2002 |
Publish date | May 9, 2002 (structure data deposition date) |
Authors | Hon, W.C. / Wilson, M.I. / Harlos, K. / Claridge, T.D. / Schofield, C.J. / Pugh, C.W. / Maxwell, P.H. / Ratcliffe, P.J. / Stuart, D.I. / Jones, E.Y. |
External links | Nature / PubMed:12050673 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-1lqb: |
Chemicals | ChemComp-SO4: ChemComp-HOH: |
Source |
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Keywords | GENE REGULATION / protein-peptide complex / tumor suppressor / cancer / proteosomal degradation / ubiquitin / prolyl hydroxylation |