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-Structure paper
Title | Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu. |
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Journal, issue, pages | Biochemistry, Vol. 39, Page 1199-1204, Year 2000 |
Publish date | Dec 3, 1999 (structure data deposition date) |
Authors | Ortlund, E. / Lacount, M.W. / Lewinski, K. / Lebioda, L. |
External links | Biochemistry / PubMed:10684596 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2 Å |
Structure data | PDB-1djo: PDB-1djp: |
Chemicals | ChemComp-CAB: ChemComp-DO2: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / PGA / Glutaminase / Asparaginase / DONV / 5-diazo-4-oxo-L-norvaline / Glutaminase-Asparaginase / suicide inhibitor / covalently bound inhibitor / HYDROLASE-HYDROLASE INHIBITOR complex / HYDROLASE / DON / 6-diazo-5-oxo-L-norvaline |