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Showing all 17 items for (author: vanderlinden & r)

PDB-5l9t:
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
Method: single particle / : Brown NG, VanderLinden R, Dube P, Haselbach D, Peters JM, Stark H, Schulman BA

PDB-5l9u:
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination
Method: single particle / : Brown NG, VanderLinden R, Dube P, Haselbach D, Peters JM, Stark H, Schulman BA

PDB-5khu:
Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution
Method: single particle / : Yamaguchi M, VanderLinden R, Dube P, Stark H, Schulman B

PDB-5khr:
Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C)
Method: single particle / : VanderLinden R, Yamaguchi M, Dube P, Haselbach D, Stark H, Schulman BA

EMDB-4021:
Human Anaphase-Promoting Complex/Cyclosome (APC/C) APC15 deletion mutant with Mitotic Checkpoint Complex (MCC) in a closed conformation.
Method: single particle / : Stark H, Schulman B, Peters JM

EMDB-4022:
Human Anaphase-Promoting Complex/Cyclosome (APC/C) APC15 deletion mutant with Mitotic Checkpoint Complex (MCC) in an open conformation.
Method: single particle / : Stark H, Schulman BA, Peters JM

EMDB-4023:
Human Anaphase-Promoting Complex/Cyclosome bound to Mitotic Checkpoint Complex (APC/C-MCC) in a closed conformation.
Method: single particle / : Stark H, Schulman BA, Peters JM

EMDB-4024:
Human Anaphase-promoting complex/Cyclosome bound to Mitotic Checkpoint Complex(APC/C-MCC) in an open conformation.
Method: single particle / : Stark H, Schulman BA, Peters JM

EMDB-4025:
Human Anaphase-promoting complex/Cyclosome (APC/C) APC15 deletion mutant bound to the E2 UBE2C (aka UBCH10) poised for ubiquitin ligation to substrate.
Method: single particle / : Stark H, Schulman BA, Peters JM

EMDB-4026:
Human Anaphase-Promoting Complex/Cyclosome (APC/C) APC15 deletion mutant bound to Mitotic Checkpoint Complex (MCC) and the E2 UBE2S poised for UB chain synthesis.
Method: single particle / : Stark H, Schulman BA, Peters JM

EMDB-4027:
Human Anaphase-Promoting Complex/Cyclosome bound to Mitotic Checkpoint Complex (APC/C-MCC) and the E2 UBE2C (aka UBCH10) poised for ubiquitination of MCC's CDC20
Method: single particle / : Stark H, Schulman BA, Peters JM

EMDB-4028:
Human Anaphase-Promoting Complex/Cyclosome (APC/C) APC15 deletion mutant bound to Mitotic Checkpoint Complex (MCC) and the E2 UBE2C (aka UBCH10) poised for ubiquitination of MCC's CDC20
Method: single particle / : Stark H, Schulman BA, Peters JM

EMDB-3432:
Anaphase-promoting complex/Cyclosome (APC/C)-CDH1-UBE2C (aka UBCH10)-substrate-Ubiquitin (variant)
Method: single particle / : Brown N, VanderLinden R, Watson E, Weissmann F, Ordureau A, Wu KP, Yu S, Mercedi P, Harrison J, Davidson I, Coudevylle R, Lu Y, Dube P, Brunner M, Grace CRR, Miller D, Haselbach D, Jarvis M, Yamaguchi M, Yanishevski D, Petzold G, Sidhu S, Kuhlman B, Kirschner M, Harper JW, Peters JM, Stark H, Schulman BA

EMDB-3433:
Anaphase-promoting complex/Cyclosome (APC/C)-CDH1-UBE2S-Ubiquitin (variant)-substrate
Method: single particle / : Brown N, VanderLinden R, Watson E, Weissmann F, Ordureau A, Wu KP, Yu S, Mercedi P, Harrison J, Davidson I, Coudevylle R, Lu Y, Dube P, Brunner M, Grace CRR, Miller D, Haselbach D, Jarvis M, Yamaguchi M, Yanishevski D, Petzold G, Sidhu S, Kuhlman B, Kirschner M, Harper JW, Peters JM, Stark H, Schulman BA

EMDB-2929:
Mechanism of Ubiquitin Ligation to a Substrate by human Anaphase-Promoting Complex
Method: single particle / : Brown N, VanderLinden R, Watson E, Qiao R, Grace CR, Yamaguchi M, Weissmann F, Frye J, Dube P, Cho SE, Actis M, Rodrigues P, Fujii N, Peters JM, Schulman BA, Stark H

EMDB-2775:
Mechanism of polyubiquitination by human Anaphase Promoting Complex: RING repurposing for ubiquitin chain assembly
Method: single particle / : Brown NG, Watson ER, Weissmann F, Jarvis MA, Vanderlinden R, Grace CRR, Frye JJ, Qiao R, Dube P, Petzold G, Cho SE, Alsharif O, Bao J, Davidson IF, Zheng J, Nourse A, Kurinov I, Peters JM, Stark H, Schulman BA

EMDB-6084:
Anaphase Promoting Complex with bound Ube2S
Method: single particle / : Brown NG, Watson ER, Weissmann F, Jarvis MA, Vanderlinden R, Grace CRR, Frye JJ, Qiao R, Dube P, Petzold G, Cho SE, Alsharif O, Bao J, Davidson IF, Zheng J, Nourse A, Kurinov I, Peters JM, Stark H, Schulman BA

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Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

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