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Showing all 33 items for (author: t. & malinauskas)

PDB-8bej:
GABA-A receptor a5 homomer - a5V3 - APO
Method: single particle / : Miller PS, Malinauskas TM, Hardwick SW, Chirgadze DY

PDB-8bha:
GABA-A receptor a5 homomer - a5V3 - Basmisanil - HR
Method: single particle / : Malinauskas TM, Wahid AA, Hardwick SW, Chirgadze DY, Miller PS

PDB-8bhb:
GABA-A receptor a5 homomer - a5V3 - RO154513
Method: single particle / : Miller PS, Malinauskas TM, Hardwick SW, Chirgadze DY, Wahid AA

PDB-8bhi:
GABA-A receptor a5 homomer - a5V3 - RO5211223
Method: single particle / : Miller PS, Malinauskas TM, Hardwick SW, Chirgadze DY

PDB-8bhk:
GABA-A receptor a5 homomer - a5V3 - Diazepam
Method: single particle / : Miller PS, Malinauskas TM, Kasaragod VB, Chirgadze DY

PDB-8bhm:
GABA-A receptor a5 homomer - a5V3 - DMCM
Method: single particle / : Miller PS, Malinauskas TM, Hardwick SW, Chirgadze DY

PDB-8bho:
GABA-A receptor a5 homomer - a5V3 - L655708
Method: single particle / : Miller PS, Malinauskas TM, Hardwick SW, Chirgadze DY

PDB-8bhq:
GABA-A receptor a5 homomer - a5V3 - RO7172670
Method: single particle / : Miller PS, Malinauskas TM, Hardwick SW, Kasaragod VB

PDB-8bhr:
GABA-A receptor a5 homomer - a5V3 - RO7015738
Method: single particle / : Miller PS, Malinauskas TM, Kasaragod VB

PDB-8bhs:
GABA-A receptor a5 homomer - a5V3 - RO4938581
Method: single particle / : Miller PS, Malinauskas TM, Hardwick SW, Chirgadze DY

PDB-7qn5:
Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with nanobody Nb25
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qn6:
Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with nanobody Nb25
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qn7:
Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with GABA, histamine and nanobody Nb25
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qn8:
Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with histamine and nanobody Nb25
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qn9:
Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with GABA, histamine and nanobody Nb25 in a pre-open/closed state
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qna:
Cryo-EM structure of human full-length alpha4beta3gamma2 GABA(A)R in complex with GABA and nanobody Nb25
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qnb:
Cryo-EM structure of human full-length beta3gamma2 GABA(A)R in complex with GABA and nanobody Nb25
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qnc:
Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with THIP (gaboxadol), histamine and nanobody Nb25
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qnd:
Cryo-EM structure of human full-length extrasynaptic beta3delta GABA(A)R in complex with THIP (gaboxadol), histamine and nanobody Nb25
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7qne:
Cryo-EM structure of human full-length synaptic alpha1beta3gamma2 GABA(A)R in complex with Ro15-4513 and megabody Mb38
Method: single particle / : Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

PDB-7ndg:
Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B
Method: single particle / : Robinson RA, Griffiths SC, van de Haar LL, Malinauskas T, van Battum EY, Zelina P, Schwab RA, Karia D, Malinauskaite L, Brignani S, van den Munkhof M, Dudukcu O, De Ruiter AA, Van den Heuvel DMA, Bishop B, Elegheert J, Aricescu AR, Pasterkamp RJ, Siebold C

PDB-7a5v:
CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc
Method: single particle / : Nakane T, Kotecha A, Sente A, Yamashita K, McMullan G, Masiulis S, Brown PMGE, Grigoras IT, Malinauskaite L, Malinauskas T, Miehling J, Yu L, Karia D, Pechnikova EV, de Jong E, Keizer J, Bischoff M, McCormack J, Tiemeijer P, Hardwick SW, Chirgadze DY, Murshudov G, Aricescu AR, Scheres SHW

PDB-7a4m:
Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A
Method: single particle / : Nakane T, Kotecha A, Sente A, Yamashita K, McMullan G, Masiulis S, Brown PMGE, Grigoras IT, Malinauskaite L, Malinauskas T, Miehling J, Yu L, Karia D, Pechnikova EV, de Jong E, Keizer J, Bischoff M, McCormack J, Tiemeijer P, Hardwick SW, Chirgadze DY, Murshudov G, Aricescu AR, Scheres SHW

PDB-6z97:
Structure of the prefusion SARS-CoV-2 spike glycoprotein
Method: single particle / : Duyvesteyn HME, Ren J, Zhao Y, Zhou D, Huo J, Carrique L, Malinauskas T, Ruza RR, Shah PNM, Fry EE, Owens R, Stuart DI

PDB-6z43:
Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex
Method: single particle / : Ruza RR, Duyvesteyn HME, Shah P, Carrique L, Ren J, Malinauskas T, Zhou D, Stuart DI, Naismith JH

PDB-6yor:
Structure of the SARS-CoV-2 spike S1 protein in complex with CR3022 Fab
Method: single particle / : Huo J, Zhao Y, Ren J, Zhou D, Duyvesteyn HME, Carrique L, Malinauskas T, Ruza RR, Shah PNM, Fry EE, Owens R, Stuart DI

PDB-6rvd:
Revised cryo-EM structure of the human 2:1 Ptch1-Shh complex
Method: single particle / : El Omari K, Rudolf AF, Kowatsch C, Malinauskas T, Kinnebrew M, Ansell TB, Bishop B, Pardon E, Schwab RA, Qian M, Duman R, Covey DF, Steyaert J, Wagner A, Sansom MSP, Rohatgi R, Siebold C

PDB-6hug:
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with picrotoxin and megabody Mb38.
Method: single particle / : Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Jasenko Z, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

PDB-6huj:
CryoEM structure of human full-length heteromeric alpha1beta3gamma2L GABA(A)R in complex with picrotoxin, GABA and megabody Mb38.
Method: single particle / : Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Jasenko Z, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

PDB-6huk:
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with bicuculline and megabody Mb38.
Method: single particle / : Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Jasenko Z, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

PDB-6huo:
CryoEM structure of human full-length heteromeric alpha1beta3gamma2L GABA(A)R in complex with alprazolam (Xanax), GABA and megabody Mb38.
Method: single particle / : Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Jasenko Z, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

PDB-6hup:
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with diazepam (Valium), GABA and megabody Mb38.
Method: single particle / : Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Jasenko Z, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

PDB-6i53:
Cryo-EM structure of the human synaptic alpha1-beta3-gamma2 GABAA receptor in complex with Megabody38 in a lipid nanodisc
Method: single particle / : Laverty D, Desai R, Uchanski T, Masiulis S, Wojciech JS, Malinauskas T, Zivanov J, Pardon E, Steyaert J, Miller KW, Aricescu AR

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Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

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  • The previous official version 1.9 will be removed from the archive.

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
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External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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