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Showing all 49 items for (author: structural & genomics & consortium & (sgc))

EMDB-18373:
cryo-EM structure of apo Clostridioides difficile toxin B
Method: single particle / : Kinsolving J, Bous J, Structural Genomics Consortium (SGC)

PDB-8qen:
cryo-EM structure of apo Clostridioides difficile toxin B
Method: single particle / : Kinsolving J, Bous J, Structural Genomics Consortium (SGC)

PDB-8sah:
Huntingtin C-HEAT domain in complex with HAP40
Method: single particle / : Harding RJ, Deme JC, Alteen MG, Arrowsmith CH, Lea SM, Structural Genomics Consortium (SGC)

EMDB-13037:
Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 1
Method: single particle / : Grieben M, Pike ACW, Saward BG, Wang D, Mukhopadhyay SMM, Moreira T, Chalk R, MacLean EM, Marsden BD, Burgess-Brown NA, Bountra C, Schofield CJ, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-7or1:
Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 1
Method: single particle / : Grieben M, Pike ACW, Saward BG, Wang D, Mukhopadhyay SMM, Moreira T, Chalk R, MacLean EM, Marsden BD, Burgess-Brown NA, Bountra C, Schofield CJ, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-12566:
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with HIP-B
Method: single particle / : Baronina A, Pike ACW, Yu X, Dong YY, Shintre CA, Tessitore A, Chu A, Rotty B, Venkaya S, Mukhopadhyay SMM, Borkowska O, Chalk R, Shrestha L, Burgess-Brown NA, Edwards AM, Arrowsmith CH, Bountra C, Han S, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-7nsg:
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with HIP-B
Method: single particle / : Baronina A, Pike ACW, Yu X, Dong YY, Shintre CA, Tessitore A, Chu A, Rotty B, Venkaya S, Mukhopadhyay SMM, Borkowska O, Chalk R, Shrestha L, Burgess-Brown NA, Edwards AM, Arrowsmith CH, Bountra C, Han S, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-12605:
Human TRiC complex in closed state with nanobody bound (Consensus Map)
Method: single particle / : Kelly JJ, Chi G, Bulawa C, Paavilainen VO, Bountra C, Huiskonen JT, Yue W, Structural Genomics Consortium (SGC)

EMDB-12606:
Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound
Method: single particle / : Kelly JJ, Chi G, Bulawa C, Paavilainen VO, Bountra C, Huiskonen JT, Yue W, Structural Genomics Consortium (SGC)

PDB-7nvl:
Human TRiC complex in closed state with nanobody bound (Consensus Map)
Method: single particle / : Kelly JJ, Chi G, Bulawa C, Paavilainen VO, Bountra C, Huiskonen JT, Yue W, Structural Genomics Consortium (SGC)

PDB-7nvm:
Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound
Method: single particle / : Kelly JJ, Chi G, Bulawa C, Paavilainen VO, Bountra C, Huiskonen JT, Yue W, Structural Genomics Consortium (SGC)

EMDB-14368:
Cryo-EM structure of USP9X
Method: single particle / : Deme JC, Halabelian L, Arrowsmith CH, Lea SM, Structural Genomics Consortium (SGC)

EMDB-14369:
Cryo-EM structure of USP9X, local refinement of monomer
Method: single particle / : Deme JC, Halabelian L, Arrowsmith CH, Lea SM, Structural Genomics Consortium (SGC)

PDB-7yxx:
Cryo-EM structure of USP9X
Method: single particle / : Deme JC, Halabelian L, Arrowsmith CH, Lea SM, Structural Genomics Consortium (SGC)

PDB-7yxy:
Cryo-EM structure of USP9X, local refinement of monomer
Method: single particle / : Deme JC, Halabelian L, Arrowsmith CH, Lea SM, Structural Genomics Consortium (SGC)

EMDB-11799:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl (Reference Map)
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

EMDB-11800:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl (Subclass)
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

PDB-7ain:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl (Reference Map)
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

PDB-7aio:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl (Subclass)
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

PDB-7aiq:
Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 1)
Method: single particle / : Ebenhoch R, Chi G, Man H, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Liko I, Tehan BG, Almeida FG, Arrowsmith CH, Tang H, Robinson CV, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, Duerr KL, Structural Genomics Consortium (SGC)

PDB-7air:
Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 2)
Method: single particle / : Ebenhoch R, Chi G, Man H, Wang D, McKinley G, Mukhopadhyay SMM, MacLean EM, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Liko I, Tehan BG, Almeida FG, Arrowsmith CH, Tang H, Robinson CV, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, Duerr KL, Structural Genomics Consortium (SGC)

EMDB-11674:
Cryo-EM structure of the cytoplasmic domain of human TRPC6
Method: single particle / : Grieben M, Pike ACW, Wang D, Mukhopadhyay SMM, Chalk R, Marsden BD, Burgess-Brown NA, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-7a6u:
Cryo-EM structure of the cytoplasmic domain of human TRPC6
Method: single particle / : Grieben M, Pike ACW, Wang D, Mukhopadhyay SMM, Chalk R, Marsden BD, Burgess-Brown NA, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-10094:
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with TFB-TBOA
Method: single particle / : Baronina A, Pike ACW, Yu X, Dong YY, Shintre CA, Tessitore A, Chu A, Rotty B, Venkaya S, Mukhopadhyay S, Borkowska O, Chalk R, Shrestha L, Burgess-Brown NA, Edwards AM, Arrowsmith CH, Bountra C, Han S, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-6s3q:
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with TFB-TBOA
Method: single particle / : Baronina A, Pike ACW, Yu X, Dong YY, Shintre CA, Tessitore A, Chu A, Rotty B, Venkaya S, Mukhopadhyay S, Borkowska O, Chalk R, Shrestha L, Burgess-Brown NA, Edwards AM, Arrowsmith CH, Bountra C, Han S, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-22106:
High resolution cryoEM structure of huntingtin in complex with HAP40
Method: single particle / : Harding RJ, Deme JC, Lea SM, Arrowsmith CH, Structural Genomics Consortium (SGC)

PDB-6x9o:
High resolution cryoEM structure of huntingtin in complex with HAP40
Method: single particle / : Harding RJ, Deme JC, Lea SM, Arrowsmith CH, Structural Genomics Consortium (SGC)

EMDB-10703:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean B, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

PDB-6y5r:
Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl
Method: single particle / : Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean B, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)

EMDB-10418:
CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2
Method: single particle / : Wang Q, Pike ACW, Grieben M, Baronina A, Nasrallah C, Shintre C, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-10419:
CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(3,5)P2
Method: single particle / : Wang Q, Pike ACW, Grieben M, Baronina A, Nasrallah C, Shintre C, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-6t9n:
CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2
Method: single particle / : Wang Q, Pike ACW, Grieben M, Baronina A, Nasrallah C, Shintre C, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-6t9o:
CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(3,5)P2
Method: single particle / : Wang Q, Pike ACW, Grieben M, Baronina A, Nasrallah C, Shintre C, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-0093:
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
Method: single particle / : Shintre CA, Pike ACW, Tessitore A, Young M, Bushell SR, Strain-Damerell C, Mukhopadhyay S, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-6gyn:
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
Method: single particle / : Shintre CA, Pike ACW, Tessitore A, Young M, Bushell SR, Strain-Damerell C, Mukhopadhyay S, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-4746:
CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form)
Method: single particle / : Pike ACW, Bushell SR, Shintre CA, Tessitore A, Baronina A, Chu A, Mukhopadhyay S, Shrestha L, Chalk R, Burgess-Brown NA, Love J, Huiskonen JT, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-4747:
CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (low Ca2+, closed form)
Method: single particle / : Pike ACW, Bushell SR, Shintre CA, Tessitore A, Chu A, Mukhopadhyay S, Shrestha L, Chalk R, Burgess-Brown NA, Love J, Huiskonen JT, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-4748:
CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form)
Method: single particle / : Pike ACW, Bushell SR, Shintre CA, Tessitore A, Chu A, Mukhopadhyay S, Shrestha L, Chalk R, Burgess-Brown NA, Love J, Huiskonen JT, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-6r7x:
CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form)
Method: single particle / : Pike ACW, Bushell SR, Shintre CA, Tessitore A, Baronina A, Chu A, Mukhopadhyay S, Shrestha L, Chalk R, Burgess-Brown NA, Love J, Huiskonen JT, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-6r7y:
CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (low Ca2+, closed form)
Method: single particle / : Pike ACW, Bushell SR, Shintre CA, Tessitore A, Chu A, Mukhopadhyay S, Shrestha L, Chalk R, Burgess-Brown NA, Love J, Huiskonen JT, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-6r7z:
CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form)
Method: single particle / : Pike ACW, Bushell SR, Shintre CA, Tessitore A, Chu A, Mukhopadhyay S, Shrestha L, Chalk R, Burgess-Brown NA, Love J, Huiskonen JT, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-0094:
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Method: single particle / : Shintre CA, Pike ACW, Tessitore A, Young M, Bushell SR, Strain-Damerell C, Mukhopadhyay S, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-6gyo:
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Method: single particle / : Shintre CA, Pike ACW, Tessitore A, Young M, Bushell SR, Strain-Damerell C, Mukhopadhyay S, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

EMDB-8200:
CryoEM structure of the human Polycystin-2/PKD2 TRP channel
Method: single particle / : Pike ACW, Grieben M, Shintre CA, Tessitore A, Shrestha L, Mukhopadhyay S, Mahajan P, Chalk R, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

PDB-5k47:
CryoEM structure of the human Polycystin-2/PKD2 TRP channel
Method: single particle / : Pike ACW, Grieben M, Shintre CA, Tessitore A, Shrestha L, Mukhopadhyay S, Mahajan P, Chalk R, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

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