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Showing 1 - 50 of 124 items for (author: sobolevsky & ai)


EMDB entry, No image

EMDB-42994:
Apo-state cryo-EM structure of human TRPV3 in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI


EMDB entry, No image

EMDB-42995:
Open-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI


EMDB entry, No image

EMDB-42996:
Inactivated-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI


EMDB entry, No image

EMDB-42997:
Open-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI


EMDB entry, No image

EMDB-42998:
Inactivated-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI


EMDB entry, No image

EMDB-43751:
TRPM7 structure in complex with anticancer agent CCT128930 in closed state
Method: single particle / : Nadezhdin KD, Sobolevsky AI

EMDB-16052:
Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4
Method: single particle / : Absmeier E, Chandrasekaran V, O'Reilly FJ, Stowell JAW, Rappsilber J, Passmore LA

EMDB-40741:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40742:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40743:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 (apo state)
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-40744:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 (apo state)
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-40745:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40746:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40747:
Structure of AMPA receptor GluA2 complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40748:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40749:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40750:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40676:
Human TRP channel TRPV6 in cNW30 nanodiscs inhibited by tetrahydrocannabivarin (THCV)
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI

EMDB-40958:
Cryo-EM structure of full-length human TRPV4 in apo state
Method: single particle / : Nadezhdin KD, Talyzina IA, Neuberger A, Sobolevsky AI

EMDB-40959:
Cryo-EM structure of human TRPV4 ankyrin repeat domain in complex with GTPase RhoA
Method: single particle / : Nadezhdin KD, Talyzina IA, Neuberger A, Sobolevsky AI

EMDB-40960:
Open-state cryo-EM structure of full-length human TRPV4 in complex with agonist 4a-PDD
Method: single particle / : Talyzina IA, Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40961:
Closed-state cryo-EM structure of full-length human TRPV4 in the presence of 4a-PDD
Method: single particle / : Talyzina IA, Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40962:
Cryo-EM structure of full-length human TRPV4 in complex with antagonist HC-067047
Method: single particle / : Talyzina IA, Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-29343:
Cryo-EM structure of human TRPV6 in complex with the natural phytoestrogen genistein
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI

EMDB-29344:
Cryo-EM structure of human TRPV6 in the open state
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI

EMDB-40496:
Cryo-EM structure of TRPM7 in MSP2N2 nanodisc in apo state
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40497:
Cryo-EM structure of TRPM7 in GDN detergent in apo state
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40498:
Cryo-EM structure of TRPM7 N1098Q mutant in GDN detergent in open state
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40499:
Cryo-EM structure of TRPM7 in MSP2N2 nanodisc in complex with agonist naltriben in open state
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40500:
Cryo-EM structure of TRPM7 in MSP2N2 nanodisc in complex with agonist naltriben in closed state
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40501:
Cryo-EM structure of TRPM7 in GDN detergent in complex with inhibitor VER155008 in closed state
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40502:
Cryo-EM structure of TRPM7 N1098Q mutant in GDN detergent in complex with inhibitor VER155008 in closed state
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40504:
Cryo-EM structure of TRPM7 N1098Q mutant in GDN detergent in complex with inhibitor NS8593 in closed state
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40505:
Cryo-EM structure of TRPM7 MHR1-3 domain
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-29981:
Cryo-EM structure of human TRPV1 in cNW11 nanodisc and soybean lipids
Method: single particle / : Neuberger A, Nadezhdin KD, Sobolevsky AI

EMDB-29982:
Cryo-EM structure of human TRPV1 in cNW11 nanodisc and POPC:POPE:POPG lipids
Method: single particle / : Neuberger A, Nadezhdin KD, Sobolevsky AI

EMDB-29983:
Cryo-EM structure of human TRPV1 in complex with the analgesic drug SB-366791
Method: single particle / : Neuberger A, Nadezhdin KD, Sobolevsky AI

PDB-8gf8:
Cryo-EM structure of human TRPV1 in cNW11 nanodisc and soybean lipids
Method: single particle / : Neuberger A, Nadezhdin KD, Sobolevsky AI

PDB-8gf9:
Cryo-EM structure of human TRPV1 in cNW11 nanodisc and POPC:POPE:POPG lipids
Method: single particle / : Neuberger A, Nadezhdin KD, Sobolevsky AI

PDB-8gfa:
Cryo-EM structure of human TRPV1 in complex with the analgesic drug SB-366791
Method: single particle / : Neuberger A, Nadezhdin KD, Sobolevsky AI

EMDB-29515:
Structure of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29516:
Structure of the amino-terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29517:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29518:
Structure of the amino terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-29519:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-29520:
Structure of the amino-terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and noncompetitive inhibitor perampanel
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-29521:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and noncompetitive inhibitor perampanel
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-26488:
Cryo-EM structure of TRPV3 in complex with the anesthetic dyclonine
Method: single particle / : Neuberger A, Nadezhdin KD, Sobolevsky AI

EMDB-26011:
Complex NNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI

EMDB-26012:
Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI

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Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
  • EM Navigator can help to find cryo-EM structure data by both pioneers.

External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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New page: Covid-19 featured information page in EM Navigator.

Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

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External links:COVID-19 featured content - PDBj / Molecule of the Month (242):Coronavirus Proteases

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