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Showing 1 - 50 of 53 items for (author: h. & r. & saibil)

PDB-8rqm:
Alpha-synuclein amyloid fibrils
Method: helical / : Saibil HR, Monistrol J

PDB-8rrr:
Alpha-synuclein amyloid fibril
Method: helical / : Saibil HR, Monistrol J

PDB-8ba8:
CryoEM structure of GroEL-ADP.BeF3-Rubisco.
Method: single particle / : Gardner S, Saibil HR

PDB-8ba9:
CryoEM structure of GroEL-GroES-ADP.AlF3-Rubisco.
Method: single particle / : Gardner S, Saibil HR

PDB-8ba7:
CryoEM structure of nucleotide-free GroEL-Rubisco.
Method: single particle / : Gardner S, Saibil HR

PDB-8a00:
Infectious mouse-adapted ME7 scrapie prion fibril purified from terminally-infected mouse brains
Method: helical / : Manka SW, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF

PDB-7qig:
Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains
Method: helical / : Manka SW, Zhang W, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF

PDB-7pag:
The pore conformation of lymphocyte perforin
Method: single particle / : Ivanova ME, Lukoyanova N, Malhotra S, Topf M, Trapani JA, Voskoboinik I, Saibil HR

PDB-6qs4:
Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Method: single particle / : Deville C, Saibil HR

PDB-6qs6:
ClpB (DWB and K476C mutant) bound to casein in presence of ATPgammaS - state KC-1
Method: single particle / : Deville C, Saibil HR

PDB-6qs7:
ClpB (DWB and K476C mutant) bound to casein in presence of ATPgammaS - state KC-2A
Method: single particle / : Deville C, Saibil HR

PDB-6qs8:
ClpB (DWB and K476C mutant) bound to casein in presence of ATPgammaS - state KC-2B
Method: single particle / : Deville C, Saibil HR

PDB-6rn2:
ClpB (DWB mutant) bound to casein in presence of ATPgammaS - state WT-1
Method: single particle / : Deville C, Saibil HR

PDB-6rn3:
ClpB (DWB mutant) bound to casein in presence of ATPgammaS - state WT-2A
Method: single particle / : Deville C, Saibil HR

PDB-6rn4:
ClpB (DWB mutant) bound to casein in presence of ATPgammaS - state WT-2B
Method: single particle / : Deville C, Saibil HR

PDB-5ofo:
Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein
Method: single particle / : Deville C, Carroni M, Franke KB, Topf M, Bukau B, Mogk A, Saibil HR

PDB-5og1:
Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state
Method: single particle / : Deville C, Carroni M, Franke KB, Topf M, Bukau B, Mogk A, Saibil HR

PDB-5fmw:
The poly-C9 component of the Complement Membrane Attack Complex
Method: single particle / : Dudkina NV, Spicer BA, Reboul CF, Conroy PJ, Lukoyanova N, Elmlund H, Law RHP, Ekkel SM, Kondos SC, Goode RJA, Ramm G, Whisstock JC, Saibil HR, Dunstone MA

PDB-4v2t:
Membrane embedded pleurotolysin pore with 13 fold symmetry
Method: single particle / : Lukoyanova N, Kondos SC, Farabella I, Law RHP, Reboul CF, Caradoc-Davies TT, Spicer BA, Kleifeld O, Perugini M, Ekkel S, Hatfaludi T, Oliver K, Hotze EM, Tweten RK, Whisstock JC, Topf M, Dunstone MA, Saibil HR

PDB-4v3a:
Membrane bound pleurotolysin prepore (TMH1 lock) trapped with engineered disulphide cross-link
Method: single particle / : Lukoyanova N, Kondos SC, Farabella I, Law RHP, Reboul CF, CaradocDavies TT, Spicer BA, Kleifeld O, Perugini M, Ekkel S, Hatfaludi T, Oliver K, Hotze EM, Tweten RK, Whisstock JC, Topf M, Dunstone MA, Saibil HR

PDB-4v3m:
Membrane bound pleurotolysin prepore (TMH2 helix lock) trapped with engineered disulphide cross-link
Method: single particle / : Lukoyanova N, Kondos SC, Farabella I, Law RHP, Reboul CF, Caradoc-Davies TT, Spicer BA, Kleifeld O, Perugini M, Ekkel S, Hatfaludi T, Oliver K, Hotze EM, Tweten RK, Whisstock JC, Topf M, Dunstone MA, Saibil HR

PDB-4v3n:
Membrane bound pleurotolysin prepore (TMH2 strand lock) trapped with engineered disulphide cross-link
Method: single particle / : Lukoyanova N, Kondos SC, Farabella I, Law RHP, Reboul CF, Caradoc-Davies TT, Spicer BA, Kleifeld O, Perugini M, Ekkel S, Hatfaludi T, Oliver K, Hotze EM, Tweten RK, Whisstock JC, Topf M, Dunstone MA, Saibil HR

PDB-4d2q:
Negative-stain electron microscopy of E. coli ClpB mutant E432A (BAP form bound to ClpP)
Method: single particle / : Carroni M, Kummer E, Oguchi Y, Clare DK, Wendler P, Sinning I, Kopp J, Mogk A, Bukau B, Saibil HR

PDB-4d2u:
Negative-stain electron microscopy of E. coli ClpB (BAP form bound to ClpP)
Method: single particle / : Carroni M, Kummer E, Oguchi Y, Clare DK, Wendler P, Sinning I, Kopp J, Mogk A, Bukau B, Saibil HR

PDB-4d2x:
Negative-stain electron microscopy of E. coli ClpB of Y503D hyperactive mutant (BAP form bound to ClpP)
Method: single particle / : Carroni M, Kummer E, Oguchi Y, Clare DK, Wendler P, Sinning I, Kopp J, Mogk A, Bukau B, Saibil HR

PDB-2m5k:
Atomic-resolution structure of a doublet cross-beta amyloid fibril
Method: single particle / : Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller S, MacPhee CE, Waudby CA, Mott HR, de Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM

PDB-2m5m:
Atomic-resolution structure of a triplet cross-beta amyloid fibril
Method: single particle / : Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller S, MacPhee CE, Waudby CA, Mott HR, de Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM

PDB-3zpk:
Atomic-resolution structure of a quadruplet cross-beta amyloid fibril.
Method: single particle / : Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller SA, MacPhee CE, Waudby CA, Mott HR, de Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM

PDB-4aaq:
ATP-triggered molecular mechanics of the chaperonin GroEL
Method: single particle / : Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR

PDB-4aar:
ATP-triggered molecular mechanics of the chaperonin GroEL
Method: single particle / : Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR

PDB-4aas:
ATP-triggered molecular mechanics of the chaperonin GroEL
Method: single particle / : Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR

PDB-4aau:
ATP-triggered molecular mechanics of the chaperonin GroEL
Method: single particle / : Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR

PDB-4ab2:
ATP-triggered molecular mechanics of the chaperonin GroEL
Method: single particle / : Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR

PDB-4ab3:
ATP-triggered molecular mechanics of the chaperonin GroEL
Method: single particle / : Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR

PDB-4a8b:
Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes
Method: single particle / : Malet H, Canellas F, Sawa J, Yan J, Thalassinos K, Ehrmann M, Clausen T, Saibil HR

PDB-4a8c:
Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with a binding peptide
Method: single particle / : Malet H, Canellas F, Sawa J, Yan J, Thalassinos K, Ehrmann M, Clausen T, Saibil HR

PDB-4a8d:
DegP dodecamer with bound OMP
Method: single particle / : Malet H, Krojer T, Sawa J, Schafer E, Saibil HR, Ehrmann M, Clausen T

PDB-4a9g:
Symmetrized cryo-EM reconstruction of E. coli DegQ 24-mer in complex with beta-casein
Method: single particle / : Malet H, Canellas F, Sawa J, Yan J, Thalassinos K, Ehrmann M, Clausen T, Saibil HR

PDB-4a8a:
Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme
Method: single particle / : Malet H, Canellas F, Sawa J, Yan J, Thalassinos K, Ehrmann M, Clausen T, Saibil HR

PDB-2zle:
Cryo-EM structure of DegP12/OMP
Method: single particle / : Schaefer E, Saibil HR

PDB-2h50:
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
Method: single particle / : White HE, Orlova EV, Chen S, Wang L, Ignatiou A, Gowen B, Stromer T, Franzmann TM, Haslbeck M, Buchner J, Saibil HR

PDB-2h53:
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
Method: single particle / : White HE, Orlova EV, Chen S, Wang L, Ignatiou A, Gowen B, Stromer T, Franzmann TM, Haslbeck M, Buchner J, Saibil HR

PDB-2cgt:
GROEL-ADP-gp31 COMPLEX
Method: single particle / : Clare DK, Bakkes PJ, van Heerikhuizen H, van der Vies SM, Saibil HR

PDB-2c7e:
REVISED ATOMIC STRUCTURE FITTING INTO A GROEL(D398A)-ATP7 CRYO-EM MAP (EMD 1047)
Method: single particle / : Ranson NA, Farr GW, Roseman AM, Gowen B, Fenton WA, Horwich AL, Saibil HR

PDB-2c7c:
FITTED COORDINATES FOR GROEL-ATP7-GROES CRYO-EM COMPLEX (EMD-1180)
Method: single particle / : Ranson NA, Clare DK, Farr GW, Houldershaw D, Horwich AL, Saibil HR

PDB-2c7d:
Fitted coordinates for GroEL-ADP7-GroES Cryo-EM complex (EMD-1181)
Method: single particle / : Ranson NA, Clare DK, Farr GW, Houldershaw D, Horwich AL, Saibil HR

PDB-2byu:
Negative stain EM reconstruction of M.tuberculosis Acr1(Hsp 16.3) fitted with wheat sHSP dimer
Method: single particle / : Kennaway CK, Benesch JLP, Gohlke U, Wang L, Robinson CV, Orlova EV, Saibil HR, Keep NH

PDB-2bk1:
The pore structure of pneumolysin, obtained by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map
Method: single particle / : Tilley SJ, Orlova EV, Gilbert RJC, Andrew PW, Saibil HR

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