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Showing 1 - 50 of 131 items for (author: brown & ed)

EMDB-44389:
Cryo-EM structure of the ZBTB5 BTB domain filament
Method: single particle / : Park J, Hunkeler M, Fischer ES

EMDB-44391:
Cryo-EM structure of the ZBTB9 BTB domain filament
Method: helical / : Park J, Hunkeler M, Fischer ES

PDB-9b9r:
Cryo-EM structure of the ZBTB5 BTB domain filament
Method: single particle / : Park J, Hunkeler M, Fischer ES

PDB-9b9v:
Cryo-EM structure of the ZBTB9 BTB domain filament
Method: helical / : Park J, Hunkeler M, Fischer ES

EMDB-17380:
Structure of human SIT1 bound to L-pipecolate (focussed map / refinement)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17381:
Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17382:
Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

PDB-8p2w:
Structure of human SIT1 (focussed map / refinement)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

PDB-8p2x:
Structure of human SIT1:ACE2 complex (open PD conformation)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

PDB-8p2y:
Structure of human SIT1:ACE2 complex (closed PD conformation)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

PDB-8p2z:
Structure of human SIT1 bound to L-pipecolate (focussed map / refinement)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

PDB-8p30:
Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

PDB-8p31:
Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17197:
Human TPC2 in Complex with Antagonist (S)-SG-094
Method: single particle / : Chi G, Pike ACW, Maclean EM, Li H, Mukhopadhyay SMM, Bohstedt T, Wang D, McKinley G, Fernandez-Cid A, Duerr K

EMDB-19108:
Human TPC2 in Complex withAntagonist (R)-SG-094
Method: single particle / : Chi G, Pike ACW, Maclean EM, Li H, Mukhopadhyay SMM, Bohstedt T, Wang D, McKinley G, Fernandez-Cid A, Duerr K

PDB-8ouo:
Human TPC2 in Complex with Antagonist (S)-SG-094
Method: single particle / : Chi G, Pike ACW, Maclean EM, Li H, Mukhopadhyay SMM, Bohstedt T, Wang D, McKinley G, Fernandez-Cid A, Duerr K

EMDB-41363:
Cryo-EM structure of DDB1deltaB-DDA1-DCAF5
Method: single particle / : Yue H, Hunkeler M, Roy Burman SS, Fischer ES

PDB-8tl6:
Cryo-EM structure of DDB1deltaB-DDA1-DCAF5
Method: single particle / : Yue H, Hunkeler M, Roy Burman SS, Fischer ES

EMDB-43083:
S. aureus TarL H300N in complex with CDP-ribitol (single tetramer)
Method: single particle / : Li FKK, Worrall LJ, Strynadka NCJ

EMDB-43084:
S. aureus TarL H300N in complex with CDP-ribitol (two tetramers with CHAPS micelle)
Method: single particle / : Li FKK, Strynadka NCJ, Worrall LJ

EMDB-16110:
Human Urea Transporter UT-A (N-Terminal Domain Model)
Method: single particle / : Chi G, Pike ACW, Maclean EM, Mukhopadhyay SMM, Bohstedt T, Scacioc A, Wang D, McKinley G, Fernandez-Cid A, Arrowsmith CH, Bountra C, Edwards A, Burgess-Brown NA, van Putte W, Duerr K

EMDB-16111:
Map of Human Urea Transporter UT-A Collected with 0 and 30 Degree Tilts
Method: single particle / : Chi G, Pike ACW, Maclean EM, Bohstedt T, Wang D, Mckinley G, Fernandez-Cid A, Mukhopadhyay SMM, Burgess-Brown NA, Edwards A, Arrowsmith C, Bountra C, Duerr KL

EMDB-16112:
Human Urea Transporter UT-B/UT1 in Complex with Inhibitor UTBinh-14
Method: single particle / : Chi G, Dietz L, Pike ACW, Maclean EM, Mukhopadhyay SMM, Bohstedt T, Wang D, Scacioc A, McKinley G, Arrowsmith CH, Edwards A, Bountra C, Fernandez-Cid A, Burgess-Brown NA, Duerr KL

PDB-8blo:
Human Urea Transporter UT-A (N-Terminal Domain Model)
Method: single particle / : Chi G, Pike ACW, Maclean EM, Mukhopadhyay SMM, Bohstedt T, Scacioc A, Wang D, McKinley G, Fernandez-Cid A, Arrowsmith CH, Bountra C, Edwards A, Burgess-Brown NA, van Putte W, Duerr K

PDB-8blp:
Human Urea Transporter UT-B/UT1 in Complex with Inhibitor UTBinh-14
Method: single particle / : Chi G, Dietz L, Pike ACW, Maclean EM, Mukhopadhyay SMM, Bohstedt T, Wang D, Scacioc A, McKinley G, Arrowsmith CH, Edwards A, Bountra C, Fernandez-Cid A, Burgess-Brown NA, Duerr KL

EMDB-17169:
Cryo-EM structure of the SARS-CoV-2 Spike bound to TMEM106B
Method: single particle / : CHEREPANOV P

EMDB-17170:
Local refinement of the SARS-CoV-2 Spike RBD bound to TMEM106B
Method: single particle / : CHEREPANOV P

EMDB-17539:
Cryo-EM structure of dimeric UBR5
Method: single particle / : Aguirre JD, Kater L, Kempf G, Cavadini S, Thoma NH

EMDB-17540:
Cryo-EM structure of full-length human UBR5 (homotetramer)
Method: single particle / : Aguirre JD, Kater L, Kempf G, Cavadini S, Thoma NH

PDB-8p82:
Cryo-EM structure of dimeric UBR5
Method: single particle / : Aguirre JD, Kater L, Kempf G, Cavadini S, Thoma NH

PDB-8p83:
Cryo-EM structure of full-length human UBR5 (homotetramer)
Method: single particle / : Aguirre JD, Kater L, Kempf G, Cavadini S, Thoma NH

EMDB-17542:
Negative stain map of UBR5 (dimer) in complex with RARA/RXRA
Method: single particle / : Aguirre JD, Cavadini S, Kempf G, Kater L, Thoma NH

EMDB-27779:
Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-8dya:
Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-14175:
Spinach 26S proteasome
Method: single particle / : Kandolf S, Grishkovskaya I

EMDB-14666:
Cryo-EM structure of Human ACE2 bound to a high-affinity SARS CoV-2 mutant
Method: single particle / : Bate N, Savva CG, Moody PCE, Brown EA, Schwabe WR, Brindle NPJ, Ball JK, Sale JE

PDB-7zdq:
Cryo-EM structure of Human ACE2 bound to a high-affinity SARS CoV-2 mutant
Method: single particle / : Bate N, Savva CG, Moody PCE, Brown EA, Schwabe WR, Brindle NPJ, Ball JK, Sale JE

EMDB-24334:
cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

EMDB-24401:
cryo-EM structure of human Gastric inhibitory polypeptide receptor GIPR bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

EMDB-24445:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R in apo form
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

EMDB-24453:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7ra3:
cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rbt:
cryo-EM structure of human Gastric inhibitory polypeptide receptor GIPR bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rg9:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R in apo form
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rgp:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
  • EM Navigator can help to find cryo-EM structure data by both pioneers.

External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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