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1O6W
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BU of 1o6w by Molmil
Solution Structure of the Prp40 WW Domain Pair of the Yeast Splicing Factor Prp40
Descriptor: PRE-MRNA PROCESSING PROTEIN PRP40
Authors:Wiesner, S, Stier, G, Sattler, M, Macias, M.J.
Deposit date:2002-10-16
Release date:2002-12-04
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Solution Structure and Ligand Recognition of the Ww Domain Pair of the Yeast Splicing Factor Prp40
J.Mol.Biol., 324, 2002
2JQZ
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BU of 2jqz by Molmil
Solution Structure of the C2 domain of human Smurf2
Descriptor: E3 ubiquitin-protein ligase SMURF2
Authors:Wiesner, S, Ogunjimi, A.A, Wang, H, Rotin, D, Sicheri, F, Wrana, J.L, Forman-Kay, J.D.
Deposit date:2007-06-15
Release date:2007-09-11
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain
Cell(Cambridge,Mass.), 130, 2007
5OAK
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BU of 5oak by Molmil
Structure of the dmPar3 PDZ1 domain in complex with the dmPar6 PBM
Descriptor: Bazooka, isoform C,LD29223p, GLYCEROL
Authors:Bruekner, S.R, Wiesner, S.
Deposit date:2017-06-22
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for the interaction between the cell polarity proteins Par3 and Par6.
Sci Signal, 11, 2018
6GF2
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BU of 6gf2 by Molmil
The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome
Descriptor: Ubiquitin D
Authors:Aichem, A, Anders, S, Catone, N, Roessler, P, Stotz, S, Berg, A, Schwab, R, Scheuermann, S, Bialas, J, Schmidtke, G, Peter, C, Groettrup, M, Wiesner, S.
Deposit date:2018-04-29
Release date:2018-08-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation.
Nat Commun, 9, 2018
6GF1
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BU of 6gf1 by Molmil
The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome
Descriptor: SULFATE ION, Ubiquitin D
Authors:Aichem, A, Anders, S, Catone, N, Roessler, P, Stotz, S, Berg, A, Schwab, R, Scheuermann, S, Bialas, J, Schmidtke, G, Peter, C, Groettrup, M, Wiesner, S.
Deposit date:2018-04-28
Release date:2018-08-29
Method:X-RAY DIFFRACTION (1.925 Å)
Cite:The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation.
Nat Commun, 9, 2018
6FYH
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BU of 6fyh by Molmil
Disulfide between ubiquitin G76C and the E3 HECT ligase Huwe1
Descriptor: E3 ubiquitin-protein ligase HUWE1, Polyubiquitin-B, SULFATE ION, ...
Authors:Jaeckl, M, Hartmann, M.D, Wiesner, S.
Deposit date:2018-03-12
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.
J. Mol. Biol., 430, 2018
6FX4
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BU of 6fx4 by Molmil
Disulfide between E3 HECT ligase Smurf2 and Ubiquitin G76C
Descriptor: E3 ubiquitin-protein ligase SMURF2, GLYCEROL, Polyubiquitin-B
Authors:Jaeckl, M, Holdermann, I, Wiesner, S.
Deposit date:2018-03-08
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.
J. Mol. Biol., 430, 2018
1ZZP
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BU of 1zzp by Molmil
Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl
Descriptor: Proto-oncogene tyrosine-protein kinase ABL1
Authors:Hantschel, O, Wiesner, S, Guttler, T, Mackereth, C.D, Rix, L.L.R, Mikes, Z, Dehne, J, Gorlich, D, Sattler, M, Superti-Furga, G.
Deposit date:2005-06-14
Release date:2005-08-30
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural Basis for the Cytoskeletal Association of Bcr-Abl/c-Abl.
Mol.Cell, 19, 2005
2B7E
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BU of 2b7e by Molmil
First FF domain of Prp40 Yeast Protein
Descriptor: Pre-mRNA processing protein PRP40
Authors:Gasch, A, Wiesner, S, Martin-Malpartida, P, Ramirez-Espain, X, Ruiz, L, Macias, M.J.
Deposit date:2005-10-04
Release date:2005-11-01
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains.
J.Biol.Chem., 281, 2006
2KIS
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BU of 2kis by Molmil
Solution structure of CA150 FF1 domain and FF1-FF2 interdomain linker
Descriptor: Transcription elongation regulator 1
Authors:Murphy, J.M, Hansen, D, Wiesner, S, Muhandiram, D, Borg, M, Smith, M.J, Sicheri, F, Kay, L.E, Forman-Kay, J.D, Pawson, T.
Deposit date:2009-05-08
Release date:2009-09-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays.
J.Mol.Biol., 393, 2009
2WRZ
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BU of 2wrz by Molmil
Crystal structure of an arabinose binding protein with designed serotonin binding site in open, ligand-free state
Descriptor: L-ARABINOSE-BINDING PERIPLASMIC PROTEIN
Authors:Schreier, B, Stumpp, C, Wiesner, S, Hocker, B.
Deposit date:2009-09-03
Release date:2009-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Computational Design of Ligand Binding is not a Solved Problem
Proc.Natl.Acad.Sci.USA, 106, 2009
2HEN
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BU of 2hen by Molmil
Crystal Structure of the EphB2 Receptor Kinase domain in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Ephrin type-B receptor 2, MAGNESIUM ION
Authors:Wybenga-Groot, L.E, Sicheri, F, Pawson, T.
Deposit date:2006-06-21
Release date:2007-02-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases
EMBO J., 25, 2006
2HEL
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BU of 2hel by Molmil
Crystal structure of a mutant EphA4 kinase domain (Y742A)
Descriptor: Eph receptor A4
Authors:Wybenga-Groot, L.E, Sicheri, F, Pawson, T.
Deposit date:2006-06-21
Release date:2007-02-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases.
EMBO J., 25, 2006
2K6D
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BU of 2k6d by Molmil
CIN85 Sh3-C domain in complex with ubiquitin
Descriptor: SH3 domain-containing kinase-binding protein 1, Ubiquitin
Authors:Forman-Kay, J, Bezsonova, I.
Deposit date:2008-07-07
Release date:2008-08-19
Last modified:2018-07-04
Method:SOLUTION NMR
Cite:Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination.
Biochemistry, 47, 2008

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