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4RGW
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BU of 4rgw by Molmil
Crystal Structure of a TAF1-TAF7 Complex in Human Transcription Factor IID
Descriptor: GLYCEROL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7
Authors:Wang, H, Curran, E.C, Hinds, T.R, Wang, E.H, Zheng, N.
Deposit date:2014-09-30
Release date:2014-12-03
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Cell Res., 24, 2014
6TYD
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BU of 6tyd by Molmil
Structure of human LDB1 in complex with SSBP2
Descriptor: LIM domain-binding protein 1, Single-stranded DNA-binding protein 2
Authors:Wang, H, Wang, Z, Xu, W.
Deposit date:2019-08-08
Release date:2020-01-01
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Crystal structure of human LDB1 in complex with SSBP2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T9K
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BU of 6t9k by Molmil
SAGA Core module
Descriptor: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ...
Authors:Wang, H, Cheung, A, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020
6T9J
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BU of 6t9j by Molmil
SAGA Tra1 module
Descriptor: Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1
Authors:Wang, H, Cheung, A, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020
6T9I
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BU of 6t9i by Molmil
cryo-EM structure of transcription coactivator SAGA
Descriptor: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ...
Authors:Wang, H, Cheung, A, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020
6T9L
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BU of 6t9l by Molmil
SAGA DUB module bound to a ubiqitinated nucleosome
Descriptor: Histone H2A, Histone H2B, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020
6HBA
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BU of 6hba by Molmil
Crystal Structure of the small subunit-like domain 1 of CcmM from Synechococcus elongatus (strain PCC 7942), thiol-oxidized form
Descriptor: Carbon dioxide concentrating mechanism protein CcmM
Authors:Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M.
Deposit date:2018-08-10
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Rubisco condensate formation by CcmM in beta-carboxysome biogenesis.
Nature, 566, 2019
6HBC
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BU of 6hbc by Molmil
Structure of the repeat unit in the network formed by CcmM and Rubisco from Synechococcus elongatus
Descriptor: Carbon dioxide concentrating mechanism protein CcmM, Ribulose 1,5-bisphosphate carboxylase small subunit, Ribulose bisphosphate carboxylase large chain
Authors:Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M.
Deposit date:2018-08-10
Release date:2018-12-12
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Rubisco condensate formation by CcmM in beta-carboxysome biogenesis.
Nature, 566, 2019
7OHA
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BU of 7oha by Molmil
nucleosome with TBP and TFIIA bound at SHL +2
Descriptor: DNA (122-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2021-05-09
Release date:2021-07-28
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7OH9
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BU of 7oh9 by Molmil
Nucleosome with TBP and TFIIA bound at SHL -6
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2021-05-09
Release date:2021-07-28
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7OHB
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BU of 7ohb by Molmil
TBP-nucleosome complex
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2021-05-10
Release date:2021-07-28
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7OHC
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BU of 7ohc by Molmil
Cryo-EM structure of nucleosome core particle composed of the Widom 601 DNA sequence
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2021-05-10
Release date:2021-07-28
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7OS7
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BU of 7os7 by Molmil
Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant
Descriptor: 30S ribosomal protein S6,30S ribosomal protein S6
Authors:Wang, H, Logan, D.T, Oliveberg, M.
Deposit date:2021-06-08
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant
To Be Published
1CGM
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BU of 1cgm by Molmil
STRUCTURE DETERMINATION OF CUCUMBER GREEN MOTTLE MOSAIC VIRUS BY X-RAY FIBER DIFFRACTION. SIGNIFICANCE FOR THE EVOLUTION OF TOBAMOVIRUSES
Descriptor: CUCUMBER GREEN MOTTLE MOSAIC VIRUS, RNA (5'-R(P*GP*AP*A)-3')
Authors:Wang, H, Stubbs, G.
Deposit date:1993-11-17
Release date:1994-04-30
Last modified:2017-11-29
Method:FIBER DIFFRACTION (3.4 Å)
Cite:Structure determination of cucumber green mottle mosaic virus by X-ray fiber diffraction. Significance for the evolution of tobamoviruses.
J.Mol.Biol., 239, 1994
2PW3
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BU of 2pw3 by Molmil
Structure of the PDE4D-cAMP complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ZINC ION, cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Authors:Wang, H, Robinson, H, Ke, H.
Deposit date:2007-05-10
Release date:2007-10-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10.
J.Mol.Biol., 371, 2007
6S01
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BU of 6s01 by Molmil
Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome
Descriptor: Histone H2A, Histone H2B 1.1, Histone H3, ...
Authors:Wang, H, Farnung, L, Dienemann, C, Cramer, P.
Deposit date:2019-06-13
Release date:2019-12-18
Last modified:2020-01-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding.
Nat.Struct.Mol.Biol., 27, 2020
2QYK
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BU of 2qyk by Molmil
Crystal structure of PDE4A10 in complex with inhibitor NPV
Descriptor: 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid, Cyclic AMP-specific phosphodiesterase HSPDE4A10, MAGNESIUM ION, ...
Authors:Wang, H, Peng, M, Chen, Y, Geng, J, Robinson, H, Houslay, M.
Deposit date:2007-08-15
Release date:2008-04-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors.
Biochem.J., 408, 2007
7SCG
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BU of 7scg by Molmil
FH210 bound Mu Opioid Receptor-Gi Protein Complex
Descriptor: (2E)-N-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-(naphthalen-1-yl)prop-2-enamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, H, Kobilka, B.
Deposit date:2021-09-28
Release date:2022-04-20
Last modified:2022-07-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure-Based Evolution of G Protein-Biased mu-Opioid Receptor Agonists.
Angew.Chem.Int.Ed.Engl., 61, 2022
6VCD
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BU of 6vcd by Molmil
Cryo-EM structure of IRP2-FBXL5-SKP1 complex
Descriptor: F-box/LRR-repeat protein 5, FE2/S2 (INORGANIC) CLUSTER, Iron-responsive element binding protein 2, ...
Authors:Wang, H, Shi, H, Zheng, N.
Deposit date:2019-12-20
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster.
Mol.Cell, 78, 2020
8EAT
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BU of 8eat by Molmil
Yeast VO missing subunits a, e, and f in complex with Vma12-22p
Descriptor: V-type proton ATPase subunit F, V-type proton ATPase subunit c, V-type proton ATPase subunit c', ...
Authors:Wang, H, Bueler, S.A, Rubinstein, J.L.
Deposit date:2022-08-29
Release date:2022-11-02
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EAS
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BU of 8eas by Molmil
Yeast VO in complex with Vma12-22p
Descriptor: V-type proton ATPase assembly factor Vma12p, V-type proton ATPase subunit F, V-type proton ATPase subunit a, ...
Authors:Wang, H, Bueler, S.A, Rubinstein, J.L.
Deposit date:2022-08-29
Release date:2022-11-02
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EAU
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BU of 8eau by Molmil
Yeast VO in complex with Vma21p
Descriptor: V-type proton ATPase subunit a, vacuolar isoform, V-type proton ATPase subunit c, ...
Authors:Wang, H, Bueler, S.A, Rubinstein, J.L.
Deposit date:2022-08-29
Release date:2022-11-02
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EAV
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BU of 8eav by Molmil
YAR027W and YAR028W in complex with c subunits from yeast VO complex
Descriptor: YAR027W or YAR028W, subunit from the c ring of yeast VO complex
Authors:Wang, H, Bueler, S.A, Rubinstein, J.L.
Deposit date:2022-08-29
Release date:2022-11-02
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
8BZN
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BU of 8bzn by Molmil
SARS-CoV-2 non-structural protein 10 (nsp10) variant T102I
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, Replicase polyprotein 1ab, ...
Authors:Wang, H, Rizvi, S.R.A, Dong, D, Lou, J, Wang, Q, Sopipong, W, Najar, F, Agarwal, P.K, Kozielski, F, Haider, S.
Deposit date:2022-12-15
Release date:2023-12-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16.
Elife, 12, 2023
1ZKL
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BU of 1zkl by Molmil
Multiple Determinants for Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases
Descriptor: 3-ISOBUTYL-1-METHYLXANTHINE, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ...
Authors:Wang, H, Liu, Y, Chen, Y, Robinson, H, Ke, H.
Deposit date:2005-05-03
Release date:2005-07-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7
J.Biol.Chem., 280, 2005

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