Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4YP2
DownloadVisualize
BU of 4yp2 by Molmil
Cleavage of nicotinamide adenine dinucleotides by the ribosome inactivating protein from Momordica charantia
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NICOTINAMIDE, Ribosome-inactivating protein momordin I
Authors:Vinkovic, M, Hussain, J, Wood, G.E, Gill, R, Wood, S.P.
Deposit date:2015-03-12
Release date:2015-05-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Cleavage of nicotinamide adenine dinucleotide by the ribosome-inactivating protein from Momordica charantia.
Acta Crystallogr.,Sect.F, 71, 2015
5CF9
DownloadVisualize
BU of 5cf9 by Molmil
Cleavage of nicotinamide adenine dinucleotide by the ribosome inactivating protein of Momordica charantia - enzyme-NADP+ co-crystallisation.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NICOTINAMIDE, Ribosome-inactivating protein momordin I
Authors:Vinkovic, M, Wood, S.P, Gill, R, Husain, J, Wood, G.E, Dunn, G.
Deposit date:2015-07-08
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Cleavage of nicotinamide adenine dinucleotide by the ribosome-inactivating protein from Momordica charantia.
Acta Crystallogr.,Sect.F, 71, 2015
4OYI
DownloadVisualize
BU of 4oyi by Molmil
Human solAC Complexed with (4-Amino-furazan-3-yl)-phenyl-methanone
Descriptor: (4-azanyl-1,2,5-oxadiazol-3-yl)-phenyl-methanone, Adenylate cyclase type 10, GLYCEROL
Authors:Vinkovic, M.
Deposit date:2014-02-12
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OYW
DownloadVisualize
BU of 4oyw by Molmil
Crystal Structure of Human Soluble Adenylate Cyclase
Descriptor: Adenylate cyclase type 10, CHLORIDE ION, GLYCEROL
Authors:Vinkovic, M.
Deposit date:2014-02-13
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OYM
DownloadVisualize
BU of 4oym by Molmil
Human solAC Complexed with (4-Amino-furazan-3-yl)-(3-methoxy-phenyl)-methanone
Descriptor: (4-azanyl-1,2,5-oxadiazol-3-yl)-(3-methoxyphenyl)methanone, Adenylate cyclase type 10, GLYCEROL
Authors:Vinkovic, M.
Deposit date:2014-02-12
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OYX
DownloadVisualize
BU of 4oyx by Molmil
Human solAC Complexed with AMPCPP
Descriptor: Adenylate cyclase type 10, CALCIUM ION, CHLORIDE ION, ...
Authors:Vinkovic, M.
Deposit date:2014-02-13
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OYA
DownloadVisualize
BU of 4oya by Molmil
Human solAC Complexed with (4-Aminofurazan-3-yl)-[3-(1H-benzoimidazol-2-ylmethoxy)phenyl]methanone
Descriptor: (4-azanyl-1,2,5-oxadiazol-3-yl)-[3-(1H-benzimidazol-2-ylmethoxy)phenyl]methanone, Adenylate cyclase type 10, GLYCEROL
Authors:Vinkovic, M.
Deposit date:2014-02-11
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OYZ
DownloadVisualize
BU of 4oyz by Molmil
Human solAC Complexed with Bicarbonate
Descriptor: Adenylate cyclase type 10, BICARBONATE ION, GLYCEROL
Authors:Vinkovic, M.
Deposit date:2014-02-13
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OYB
DownloadVisualize
BU of 4oyb by Molmil
Crystal Structure Analysis of the solAC
Descriptor: Adenylate cyclase type 10, GLYCEROL, ethyl 2-[3-[(4-azanyl-1,2,5-oxadiazol-3-yl)carbonyl]phenoxy]ethanoate
Authors:Vinkovic, M.
Deposit date:2014-02-11
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OYO
DownloadVisualize
BU of 4oyo by Molmil
Human solAC Complexed with 4-(2-Chlorophenyl)-3-methyl-1H-pyrazole
Descriptor: 4-(2-chlorophenyl)-5-methyl-1H-pyrazole, Adenylate cyclase type 10, GLYCEROL
Authors:Vinkovic, M.
Deposit date:2014-02-12
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OZ3
DownloadVisualize
BU of 4oz3 by Molmil
Human solAC Complexed with 4-phenyl-3-(trifluoromethyl)-1H-pyrazole
Descriptor: 4-phenyl-3-(trifluoromethyl)-1H-pyrazole, Adenylate cyclase type 10, GLYCEROL
Authors:Vinkovic, M.
Deposit date:2014-02-13
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OYP
DownloadVisualize
BU of 4oyp by Molmil
Human solAC Complexed with 1-Benzofuran-2-carboxylic acid
Descriptor: 1-benzofuran-2-carboxylic acid, Adenylate cyclase type 10, CHLORIDE ION
Authors:Vinkovic, M.
Deposit date:2014-02-12
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
4OZ2
DownloadVisualize
BU of 4oz2 by Molmil
Human solAC Complexed with 4-(4-Fluorophenyl)-3-methyl-1H-pyrazole
Descriptor: 4-(4-fluorophenyl)-3-methyl-1H-pyrazole, Adenylate cyclase type 10, CHLORIDE ION, ...
Authors:Vinkovic, M.
Deposit date:2014-02-13
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
1KS9
DownloadVisualize
BU of 1ks9 by Molmil
Ketopantoate Reductase from Escherichia coli
Descriptor: 2-DEHYDROPANTOATE 2-REDUCTASE
Authors:Matak-Vinkovic, D, Vinkovic, M, Saldanha, S.A, Ashurst, J.A, von Delft, F, Inoue, T, Miguel, R.N, Smith, A.G, Blundell, T.L, Abell, C.
Deposit date:2002-01-11
Release date:2002-01-25
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism.
Biochemistry, 40, 2001
1PQF
DownloadVisualize
BU of 1pqf by Molmil
Glycine 24 to Serine mutation of aspartate decarboxylase
Descriptor: Aspartate 1-decarboxylase, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-18
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PYQ
DownloadVisualize
BU of 1pyq by Molmil
Unprocessed Aspartate Decarboxylase Mutant, with Alanine inserted at position 24
Descriptor: Aspartate 1-decarboxylase, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-07-09
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PPY
DownloadVisualize
BU of 1ppy by Molmil
Native precursor of pyruvoyl dependent Aspartate decarboxylase
Descriptor: Aspartate 1-decarboxylase precursor, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-17
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PYU
DownloadVisualize
BU of 1pyu by Molmil
Processed Aspartate Decarboxylase Mutant with Ser25 mutated to Cys
Descriptor: Aspartate 1-decarboxylase alfa chain, Aspartate 1-decarboxylase beta chain, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-07-09
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PQE
DownloadVisualize
BU of 1pqe by Molmil
S25A mutant of pyruvoyl dependent aspartate decarboxylase
Descriptor: Aspartate 1-decarboxylase
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-18
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PT0
DownloadVisualize
BU of 1pt0 by Molmil
Unprocessed Pyruvoyl Dependent Aspartate Decarboxylase with an Alanine insertion at position 26
Descriptor: Aspartate 1-decarboxylase, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-22
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PT1
DownloadVisualize
BU of 1pt1 by Molmil
Unprocessed Pyruvoyl Dependent Aspartate Decarboxylase with Histidine 11 Mutated to Alanine
Descriptor: Aspartate 1-decarboxylase, SULFATE ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-22
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
1PQH
DownloadVisualize
BU of 1pqh by Molmil
Serine 25 to Threonine mutation of aspartate decarboxylase
Descriptor: Aspartate 1-decarboxylase, MALONIC ACID, SODIUM ION
Authors:Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
Deposit date:2003-06-18
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
Embo J., 22, 2003
2W1D
DownloadVisualize
BU of 2w1d by Molmil
Structure determination of Aurora Kinase in complex with inhibitor
Descriptor: 2-(1H-pyrazol-3-yl)-1H-benzimidazole, SERINE/THREONINE-PROTEIN KINASE 6
Authors:Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G.
Deposit date:2008-10-17
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity.
J.Med.Chem., 52, 2009
2W1F
DownloadVisualize
BU of 2w1f by Molmil
Structure determination of Aurora Kinase in complex with inhibitor
Descriptor: N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE, SERINE/THREONINE-PROTEIN KINASE 6
Authors:Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G.
Deposit date:2008-10-17
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity.
J.Med.Chem., 52, 2009
2W1G
DownloadVisualize
BU of 2w1g by Molmil
Structure determination of Aurora Kinase in complex with inhibitor
Descriptor: 2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-6-(MORPHOLIN-4-IUM-4-YLMETHYL)-1H-3,1-BENZIMIDAZOL-3-IUM, SERINE/THREONINE-PROTEIN KINASE 6
Authors:Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G.
Deposit date:2008-10-17
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity.
J.Med.Chem., 52, 2009

 

12>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon