6L93
 
 | |
8IPA
 | | Wheat 80S ribosome stalled on AUG-Stop boron dependently with cycloheximide | | Descriptor: | 18S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 40S ribosomal protein eL8, ... | | Authors: | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | | Deposit date: | 2023-03-14 | | Release date: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Nat.Chem.Biol., 2024
|
|
8IP9
 | | Wheat 40S ribosome in complex with a tRNAi | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S23, 40S ribosomal protein eS1, ... | | Authors: | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | | Deposit date: | 2023-03-14 | | Release date: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Nat.Chem.Biol., 2024
|
|
8IP8
 | | Wheat 80S ribosome stalled on AUG-Stop boron dependently | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein eL8, 40S ribosomal protein eS1, ... | | Authors: | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | | Deposit date: | 2023-03-14 | | Release date: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Nat.Chem.Biol., 2024
|
|
8IPB
 | | Wheat 80S ribosome pausing on AUG-Stop with cycloheximide | | Descriptor: | 18S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 40S ribosomal protein eL8, ... | | Authors: | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | | Deposit date: | 2023-03-14 | | Release date: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Nat.Chem.Biol., 2024
|
|
2ROR
 | | Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76 | | Descriptor: | 15-meric peptide from Lymphocyte cytosolic protein 2, Proto-oncogene vav | | Authors: | Tanaka, M, Kasai, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2008-04-08 | | Release date: | 2009-04-21 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76
To be Published
|
|
2RSY
 | | Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp | | Descriptor: | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Tyrosine-protein kinase CSK | | Authors: | Tanaka, H, Akagi, K, Oneyama, C, Tanaka, M, Sasaki, Y, Kanou, T, Lee, Y, Yokogawa, D, Debenecker, M, Nakagawa, A, Okada, M, Ikegami, T. | | Deposit date: | 2012-09-10 | | Release date: | 2013-04-10 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains.
J.Biol.Chem., 288, 2013
|
|
1J3A
 | | Crystal structure of ribosomal protein L13 from Pyrococcus horikoshii | | Descriptor: | 50S ribosomal protein L13P | | Authors: | Nakashima, T, Tanaka, M, Kazama, T, Kawamura, S, Kimura, M, Yao, M, Tanaka, I. | | Deposit date: | 2003-01-21 | | Release date: | 2003-02-04 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of ribosomal protein L13 from hyperthermophilic archaeon Pyrococcus horikoshii
To be Published
|
|
3ED1
 | | Crystal Structure of Rice GID1 complexed with GA3 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GIBBERELLIN A3, Gibberellin receptor GID1, ... | | Authors: | Shimada, A, Nakatsu, T, Ueguchi-Tanaka, M, Kato, H, Matsuoka, M. | | Deposit date: | 2008-09-02 | | Release date: | 2008-11-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for gibberellin recognition by its receptor GID1.
Nature, 456, 2008
|
|
3EBL
 | | Crystal Structure of Rice GID1 complexed with GA4 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GIBBERELLIN A4, Gibberellin receptor GID1, ... | | Authors: | Shimada, A, Nakatsu, T, Ueguchi-Tanaka, M, Kato, H, Matsuoka, M. | | Deposit date: | 2008-08-28 | | Release date: | 2008-11-25 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for gibberellin recognition by its receptor GID1.
Nature, 456, 2008
|
|
4J70
 | | Yeast 20S proteasome in complex with the belactosin derivative 3e | | Descriptor: | Proteasome component C1, Proteasome component C11, Proteasome component C5, ... | | Authors: | Kawamura, S, Unno, Y, List, A, Tanaka, M, Sasaki, T, Arisawa, M, Asai, A, Groll, M, Shuto, S. | | Deposit date: | 2013-02-12 | | Release date: | 2013-04-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Potent Proteasome Inhibitors Derived from the Unnatural cis-Cyclopropane Isomer of Belactosin A: Synthesis, Biological Activity, and Mode of Action.
J.Med.Chem., 56, 2013
|
|
6KSL
 | | Staphylococcus aureus lipase - S116A inactive mutant | | Descriptor: | CALCIUM ION, LAURIC ACID, Lipase 2, ... | | Authors: | Kitadokoro, K, Tanaka, M, Kamitani, S. | | Deposit date: | 2019-08-24 | | Release date: | 2020-04-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat.
Sci Rep, 10, 2020
|
|
7EKD
 | | Crystal structure of gibberellin 3-oxidase 2 (GA3ox2) in rice | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-OXOGLUTARIC ACID, Gibberellin 3-beta-dioxygenase 2, ... | | Authors: | Takehara, S, Kawai, K, Mikami, B, Ueguchi-Tanaka, M. | | Deposit date: | 2021-04-05 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.899 Å) | | Cite: | Evolutionary alterations in gene expression and enzymatic activities of gibberellin 3-oxidase 1 in Oryza.
Commun Biol, 5, 2022
|
|
6KU3
 | | Crystal structure of gibberellin 2-oxidase3 (GA2ox3)in rice | | Descriptor: | 2-OXOGLUTARIC ACID, GIBBERELLIN A4, GLYCEROL, ... | | Authors: | Takehara, S, Mikami, B, Sakuraba, S, Matsuoka, M, Ueguchi-Tanaka, M. | | Deposit date: | 2019-08-30 | | Release date: | 2020-05-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | A common allosteric mechanism regulates homeostatic inactivation of auxin and gibberellin.
Nat Commun, 11, 2020
|
|
6KUN
 | | Crystal structure of dioxygenase for auxin oxidation (DAO) in rice | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent dioxygenase DAO, ... | | Authors: | Takehara, S, Mikami, B, Sakuraba, S, Matsuoka, M, Ueguchi-Tanaka, M. | | Deposit date: | 2019-09-02 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.002 Å) | | Cite: | A common allosteric mechanism regulates homeostatic inactivation of auxin and gibberellin.
Nat Commun, 11, 2020
|
|
1TO4
 | | Structure of the cytosolic Cu,Zn SOD from S. mansoni | | Descriptor: | COPPER (II) ION, Superoxide dismutase, ZINC ION | | Authors: | Cardoso, R.M.F, Silva, C.H.T.P, Ulian de Araujo, A.P, Tanaka, T, Tanaka, M, Garratt, R.C. | | Deposit date: | 2004-06-12 | | Release date: | 2004-08-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structure of the cytosolic Cu,Zn superoxide dismutase from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
1TO5
 | | Structure of the cytosolic Cu,Zn SOD from S. mansoni | | Descriptor: | ACETATE ION, COPPER (II) ION, Superoxide dismutase, ... | | Authors: | Cardoso, R.M.F, Silva, C.H.T.P, Ulian de Araujo, A.P, Tanaka, T, Tanaka, M, Garratt, R.C. | | Deposit date: | 2004-06-12 | | Release date: | 2004-08-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the cytosolic Cu,Zn superoxide dismutase from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
6KSM
 | | Staphylococcus aureus lipase -Orlistat complex | | Descriptor: | (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, CALCIUM ION, LAURIC ACID, ... | | Authors: | Kitadokoro, K, Tanaka, M, Kamitani, S. | | Deposit date: | 2019-08-24 | | Release date: | 2020-04-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat.
Sci Rep, 10, 2020
|
|
6KSI
 | | Staphylococcus aureus lipase - native | | Descriptor: | CALCIUM ION, HEXANOIC ACID, LAURIC ACID, ... | | Authors: | Kitadokoro, K, Tanaka, M, Kamitani, S. | | Deposit date: | 2019-08-24 | | Release date: | 2020-04-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat.
Sci Rep, 10, 2020
|
|
3WY8
 | | Crystal Structure of Protease Anisep from Arthrobacter Nicotinovorans | | Descriptor: | Serine protease | | Authors: | Sone, T, Haraguchi, Y, Kuwahara, A, Ose, T, Takano, M, Abe, A, Tanaka, M, Tanaka, I, Asano, K. | | Deposit date: | 2014-08-20 | | Release date: | 2015-08-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural characterization reveals the keratinolytic activity of an arthrobacter nicotinovorans protease.
Protein Pept.Lett., 22, 2015
|
|
3WOW
 | | Crystal structure of human CK2a with AMPPNP | | Descriptor: | 1,2-ETHANEDIOL, Casein kinase II subunit alpha, MAGNESIUM ION, ... | | Authors: | Kinoshita, T, Nakaniwa, T, Sekiguchi, Y, Sogabe, Y, Sakurai, A, Nakamura, S, Nakanishi, I, Shimada, K, Tanaka, M. | | Deposit date: | 2014-01-06 | | Release date: | 2015-02-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A hydrophobic residue divergence of CK2a contribute to a species-dependent variation for apigenin binding mode but not for an ATP analogue
To be Published
|
|
5JWM
 | | Bivalent BET Bromodomain Inhibition | | Descriptor: | 2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]-~{N}-[2-[2-[2-[2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]ethanamide, Bromodomain-containing protein 4 | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2016-05-12 | | Release date: | 2016-07-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Design and characterization of bivalent BET inhibitors.
Nat.Chem.Biol., 12, 2016
|
|
1WMA
 | | Crystal structure of human CBR1 in complex with Hydroxy-PP | | Descriptor: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 3-(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)PHENOL, ... | | Authors: | Rauh, D, Bateman, R, Shokat, K.M. | | Deposit date: | 2004-07-06 | | Release date: | 2005-04-26 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | An unbiased cell morphology-based screen for new, biologically active small molecules
Plos Biol., 3, 2005
|
|
3AA4
 | | A52V E.coli RNase HI | | Descriptor: | Ribonuclease HI | | Authors: | Takano, K. | | Deposit date: | 2009-11-11 | | Release date: | 2010-10-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI
Protein Pept.Lett., 17, 2010
|
|
3AA3
 | | A52L E. coli RNase HI | | Descriptor: | Ribonuclease HI | | Authors: | Takano, K. | | Deposit date: | 2009-11-11 | | Release date: | 2010-10-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI
Protein Pept.Lett., 17, 2010
|
|
