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8DTM
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BU of 8dtm by Molmil
Cryo-EM structure of insulin receptor (IR) bound with S597 component 2
Descriptor: Insulin mimetic peptide S597 component 2, Insulin receptor
Authors:Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
Deposit date:2022-07-26
Release date:2022-09-07
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
8DTL
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BU of 8dtl by Molmil
Cryo-EM structure of insulin receptor (IR) bound with S597 peptide
Descriptor: Insulin mimetic peptide S597, Insulin receptor
Authors:Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
Deposit date:2022-07-25
Release date:2022-09-07
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
7SMQ
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BU of 7smq by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7SMT
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BU of 7smt by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine and carbachol
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7SMM
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BU of 7smm by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in apo form
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7SMS
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BU of 7sms by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7SMR
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BU of 7smr by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with carbachol, desensitized state
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7U16
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BU of 7u16 by Molmil
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U17
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BU of 7u17 by Molmil
TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U18
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BU of 7u18 by Molmil
TMEM106B(120-254) T185S protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, TMEM106B protein
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-20
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U0Z
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BU of 7u0z by Molmil
High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1
Descriptor: Isoform Tau-E of Microtubule-associated protein tau
Authors:FItzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U12
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BU of 7u12 by Molmil
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U13
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BU of 7u13 by Molmil
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U14
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BU of 7u14 by Molmil
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U10
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BU of 7u10 by Molmil
TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U11
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BU of 7u11 by Molmil
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U15
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BU of 7u15 by Molmil
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
Deposit date:2022-02-19
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
1AIG
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BU of 1aig by Molmil
PHOTOSYNTHETIC REACTION CENTER FROM RHODOBACTER SPHAEROIDES IN THE D+QB-CHARGE SEPARATED STATE
Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ...
Authors:Stowell, M.H.B, Mcphillips, T.M, Soltis, S.M, Rees, D.C, Abresch, E, Feher, G.
Deposit date:1997-04-17
Release date:1997-10-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Light-induced structural changes in photosynthetic reaction center: implications for mechanism of electron-proton transfer.
Science, 276, 1997
1AIJ
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BU of 1aij by Molmil
PHOTOSYNTHETIC REACTION CENTER FROM RHODOBACTER SPHAEROIDES IN THE CHARGE-NEUTRAL DQAQB STATE
Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ...
Authors:Stowell, M.H.B, Mcphillips, T.M, Soltis, S.M, Rees, D.C, Abresch, E, Feher, G.
Deposit date:1997-04-18
Release date:1997-10-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Light-induced structural changes in photosynthetic reaction center: implications for mechanism of electron-proton transfer.
Science, 276, 1997
6UWZ
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BU of 6uwz by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with alpha-bungarotoxin
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ...
Authors:Rahman, M.M, Teng, J, Worrell, B.T, Noveillo, C.M, Lee, M, Karlin, A, Stowell, M, Hibbs, R.E.
Deposit date:2019-11-06
Release date:2020-04-15
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins.
Neuron, 106, 2020
6OCE
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BU of 6oce by Molmil
Structure of the rice hyperosmolality-gated ion channel OSCA1.2
Descriptor: stress-gated cation channel 1.2
Authors:Maity, K, Heumann, J.M, McGrath, A.P, Chang, G, Stowell, M.H.
Deposit date:2019-03-23
Release date:2019-07-03
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Cryo-EM structure of OSCA1.2 fromOryza sativaelucidates the mechanical basis of potential membrane hyperosmolality gating.
Proc.Natl.Acad.Sci.USA, 116, 2019
3MIN
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BU of 3min by Molmil
NITROGENASE MOFE PROTEIN FROM AZOTOBACTER VINELANDII, OXIDIZED STATE
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE(8)-S(7) CLUSTER, ...
Authors:Peters, J.W, Stowell, M.H.B, Soltis, S.M, Day, M.W, Kim, J, Rees, D.C.
Deposit date:1996-12-20
Release date:1997-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Redox-dependent structural changes in the nitrogenase P-cluster.
Biochemistry, 36, 1997
2MIN
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BU of 2min by Molmil
NITROGENASE MOFE PROTEIN FROM AZOTOBACTER VINELANDII, OXIDIZED STATE
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE(8)-S(7) CLUSTER, ...
Authors:Peters, J.W, Stowell, M.H.B, Soltis, S.M, Day, M.W, Kim, J, Rees, D.C.
Deposit date:1996-12-20
Release date:1997-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Redox-dependent structural changes in the nitrogenase P-cluster.
Biochemistry, 36, 1997
1LRV
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BU of 1lrv by Molmil
A LEUCINE-RICH REPEAT VARIANT WITH A NOVEL REPETITIVE PROTEIN STRUCTURAL MOTIF
Descriptor: LEUCINE-RICH REPEAT VARIANT
Authors:Peters, J.W, Stowell, M.H.B, Rees, D.C.
Deposit date:1996-11-05
Release date:1997-03-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A leucine-rich repeat variant with a novel repetitive protein structural motif.
Nat.Struct.Biol., 3, 1996
1DV3
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BU of 1dv3 by Molmil
PHOTOSYNTHETIC REACTION CENTER FROM RHODOBACTER SPHAEROIDES IN THE CHARGE-SEPARATED D+QAQB-STATE WITH THE PROTON TRANSFER INHIBITOR CD2+
Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CADMIUM ION, ...
Authors:Axelrod, H.L, Abresch, E.C, Paddock, M.L, Okamura, M.Y, Feher, G.
Deposit date:2000-01-19
Release date:2000-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Determination of the binding sites of the proton transfer inhibitors Cd2+ and Zn2+ in bacterial reaction centers.
Proc.Natl.Acad.Sci.USA, 97, 2000

 

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