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2WVJ
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BU of 2wvj by Molmil
Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine towards the Nucleoside Analogue Azidothymidine
Descriptor: MAGNESIUM ION, THYMIDINE KINASE, CYTOSOLIC, ...
Authors:Skovgaard, T, Uhlin, U, Munch-Petersen, B.
Deposit date:2009-10-17
Release date:2009-10-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Comparative Active-Site Mutation Study of Human and Caenorhabditis Elegans Thymidine Kinase 1.
FEBS J., 279, 2012
4TXC
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BU of 4txc by Molmil
Crystal Structure of DAPK1 kinase domain in complex with a small molecule inhibitor
Descriptor: 1,2-ETHANEDIOL, 4-(3-{3-[(R)-{[2-(dimethylamino)ethyl]amino}(hydroxy)methyl]phenyl}imidazo[1,2-b]pyridazin-6-yl)-2-methoxyphenol, Death-associated protein kinase 1
Authors:Sorrell, F.J, Krojer, T, Wilbek, T.S, Skovgaard, T, Berthelsen, J, Dixon-Clarke, S, Chalk, R, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Stromgaard, K, Knapp, S.
Deposit date:2014-07-03
Release date:2014-07-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1.
Chembiochem, 16, 2015
1ZMX
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BU of 1zmx by Molmil
Crystal structure of D. melanogaster deoxyribonucleoside kinase N64D mutant in complex with thymidine
Descriptor: Deoxynucleoside kinase, SULFATE ION, THYMIDINE
Authors:Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H.
Deposit date:2005-05-11
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
1ZM7
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BU of 1zm7 by Molmil
Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP
Descriptor: Deoxynucleoside kinase, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
Authors:Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H.
Deposit date:2005-05-10
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005

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