4AKX
 
 | | Structure of the heterodimeric complex ExoU-SpcU from the type III secretion system (T3SS) of Pseudomonas aeruginosa | | Descriptor: | EXOU, SPCU | | Authors: | Gendrin, C, Contreras-Martel, C, Bouillot, S, Elsen, S, Lemaire, D, Skoufias, D.A, Huber, P, Attree, I, Dessen, A. | | Deposit date: | 2012-02-29 | | Release date: | 2012-04-18 | | Last modified: | 2012-05-30 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin Exou from Pseudomonas Aeruginosa
Plos Pathog., 8, 2012
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6Y1I
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6TRL
 | | Human Eg5 motor domain mutant Y82F | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Kinesin-like protein KIF11, ... | | Authors: | Garcia-Saez, I, Skoufias, D.A. | | Deposit date: | 2019-12-19 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Human Eg5 motor domain mutant Y82F
To Be Published
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6TLE
 | | Human Eg5 motor domain mutant E344K | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ... | | Authors: | Garcia-Saez, I, Skoufias, D.A. | | Deposit date: | 2019-12-02 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Human Eg5 motor domain mutant E344K
To Be Published
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1E31
 | | SURVIVIN DIMER H. SAPIENS | | Descriptor: | APOPTOSIS INHIBITOR SURVIVIN, COBALT (II) ION, ZINC ION | | Authors: | Chantalat, L, Skoufias, D.A, Margolis, R.L, Dideberg, O. | | Deposit date: | 2000-06-04 | | Release date: | 2001-01-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Crystal Structure of Human Survivin Reveals a Bow Tie-Shaped Dimer with Two Unusual Alpha-Helical Extensions
Mol.Cell, 6, 2000
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3MS6
 | | Crystal structure of Hepatitis B X-Interacting Protein (HBXIP) | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Hepatitis B virus X-interacting protein, ... | | Authors: | Garcia-Saez, I, Skoufias, D. | | Deposit date: | 2010-04-29 | | Release date: | 2010-11-10 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.085 Å) | | Cite: | Structural Characterization of HBXIP: The Protein That Interacts with the Anti-Apoptotic Protein Survivin and the Oncogenic Viral Protein HBx.
J.Mol.Biol., 405, 2011
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3MSH
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5NL0
 | | Crystal structure of a 197-bp palindromic 601L nucleosome in complex with linker histone H1 | | Descriptor: | DNA (197-MER), Histone H1.0-B, Histone H2A type 1, ... | | Authors: | Garcia-Saez, I, Petosa, C, Dimitrov, S. | | Deposit date: | 2017-04-03 | | Release date: | 2017-05-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (5.4 Å) | | Cite: | Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.
Mol. Cell, 66, 2017
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6HKT
 | | Structure of an H1-bound 6-nucleosome array | | Descriptor: | DNA (1122-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | Authors: | Garcia-Saez, I, Dimitrov, S, Petosa, C. | | Deposit date: | 2018-09-08 | | Release date: | 2018-10-31 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (9.7 Å) | | Cite: | Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation.
Mol. Cell, 72, 2018
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6HKY
 | | Eg5-inhibitor complex | | Descriptor: | (2~{S})-2-(3-azanylpropyl)-5-[2,5-bis(fluoranyl)phenyl]-~{N}-methoxy-~{N}-methyl-2-phenyl-1,3,4-thiadiazole-3-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | | Authors: | Talapatra, S.K, Kozielski, F. | | Deposit date: | 2018-09-09 | | Release date: | 2019-09-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5-Inhibitor Complexes.
Mol.Cancer Ther., 18, 2019
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6HKX
 | | Eg5-inhibitor complex | | Descriptor: | (2~{S})-2-(3-azanylpropyl)-5-[2,5-bis(fluoranyl)phenyl]-~{N}-methoxy-~{N}-methyl-2-phenyl-1,3,4-thiadiazole-3-carboxamide, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Talapatra, S.K, Kozielski, F. | | Deposit date: | 2018-09-09 | | Release date: | 2019-09-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5-Inhibitor Complexes.
Mol.Cancer Ther., 18, 2019
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