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7RW6
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BU of 7rw6 by Molmil
BORF2-APOBEC3Bctd Complex
Descriptor: DNA dC->dU-editing enzyme APOBEC-3B, Maltose/maltodextrin-binding periplasmic protein,Ribonucleoside-diphosphate reductase large subunit, ZINC ION
Authors:Shaban, N.M, Yan, R, Shi, K, McLellan, J.S, Yu, Z, Harris, R.S.
Deposit date:2021-08-19
Release date:2022-04-27
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.
Sci Adv, 8, 2022
5HX5
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BU of 5hx5 by Molmil
APOBEC3F Catalytic Domain Crystal Structure
Descriptor: DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION
Authors:Shaban, N.M, Shi, K, Aihara, H, Harris, R.S.
Deposit date:2016-01-29
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure.
J.Mol.Biol., 428, 2016
5HX4
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Zinc-Free APOBEC3F Catalytic Domain Crystal Structure
Descriptor: DNA dC->dU-editing enzyme APOBEC-3F
Authors:Shaban, N.M, Shi, K, Aihara, H, Harris, R.S.
Deposit date:2016-01-29
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure.
J.Mol.Biol., 428, 2016
6B0B
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Crystal structure of human APOBEC3H
Descriptor: APOBEC3H, MCherry, RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Shaban, N.M, Shi, K, Banerjee, S, Harris, R.S, Aihara, H.
Deposit date:2017-09-14
Release date:2017-10-25
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (3.2800622 Å)
Cite:The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.
Mol. Cell, 69, 2018
6BBO
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Crystal structure of human APOBEC3H/RNA complex
Descriptor: APOBEC3H, GLYCEROL, MCherry fluorescent protein, ...
Authors:Shaban, N.M, Shi, K, Banerjee, S, Harris, R.S, Aihara, H.
Deposit date:2017-10-19
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.428 Å)
Cite:The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.
Mol. Cell, 69, 2018
4WKJ
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BU of 4wkj by Molmil
Crystallographic Structure of a Dodecameric RNA-DNA Hybrid
Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), MAGNESIUM ION, RNA (5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3')
Authors:Davis, R.R, Shaban, N.M, Perrino, F.W, Hollis, T.
Deposit date:2014-10-02
Release date:2014-10-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of RNA-DNA duplex provides insight into conformational changes induced by RNase H binding.
Cell Cycle, 14, 2015
3KIO
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BU of 3kio by Molmil
mouse RNase H2 complex
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Shaban, N, Harvey, S, Perrino, F.W, Hollis, T.
Deposit date:2009-11-02
Release date:2009-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction.
J.Biol.Chem., 285, 2010
3P5J
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The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Bubeck, D, Graham, S.C, Jones, E.Y.
Deposit date:2010-10-08
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
5SWW
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Crystal Structure of Human APOBEC3A complexed with ssDNA
Descriptor: DNA 15-Mer, DNA dC->dU-editing enzyme APOBEC-3A, GLYCEROL, ...
Authors:Shi, K, Banerjee, S, Kurahashi, K, Aihara, H.
Deposit date:2016-08-09
Release date:2016-12-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.151 Å)
Cite:Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
Nat. Struct. Mol. Biol., 24, 2017
5TD5
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Crystal Structure of Human APOBEC3B variant complexed with ssDNA
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(P*TP*TP*CP*AP*T)-3'), ...
Authors:Shi, K, Banerjee, S, Kurahashi, K, Aihara, H.
Deposit date:2016-09-16
Release date:2016-12-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.718 Å)
Cite:Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
Nat. Struct. Mol. Biol., 24, 2017

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