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3ZGC
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BU of 3zgc by Molmil
crystal structure of the KEAP1-NEH2 complex
Descriptor: ACETATE ION, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1, NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2
Authors:Hoerer, S, Reinert, D, Ostmann, K, Hoevels, Y, Nar, H.
Deposit date:2012-12-17
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
Acta Crystallogr.,Sect.F, 69, 2013
3ZGD
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BU of 3zgd by Molmil
crystal structure of a KEAP1 mutant
Descriptor: ACETATE ION, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1, SODIUM ION
Authors:Hoerer, S, Reinert, D, Ostmann, K, Hoevels, Y, Nar, H.
Deposit date:2012-12-17
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
Acta Crystallogr.,Sect.F, 69, 2013
4BB9
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BU of 4bb9 by Molmil
Crystal structure of glucokinase regulatory protein complexed to fructose-1-phosphate
Descriptor: 1-O-phosphono-beta-D-fructopyranose, CALCIUM ION, GLUCOKINASE REGULATORY PROTEIN
Authors:Pautsch, A, Stadler, N, Loehle, A, Lenter, M, Rist, W, Berg, A, Glocker, L, Nar, H, Reinert, D, Heckel, A, Schnapp, G, Kauschke, S.G.
Deposit date:2012-09-21
Release date:2013-05-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Crystal Structure of Glucokinase Regulatory Protein.
Biochemistry, 52, 2013
6Z86
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BU of 6z86 by Molmil
human GTP cyclohydrolase I in complex with 7-deaza-GTP
Descriptor: 7-deaza-GTP, GTP cyclohydrolase 1, ZINC ION
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-06-02
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Z88
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BU of 6z88 by Molmil
human GTP cyclohydrolase I in complex with allosteric inhibitor
Descriptor: 5-azanyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-dione, GTP cyclohydrolase 1, ZINC ION
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-06-02
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.687 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Z89
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BU of 6z89 by Molmil
human GTP cyclohydrolase I in complex with allosteric inhibitor
Descriptor: 5-azanyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-dione, GTP cyclohydrolase 1, ZINC ION
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-06-02
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.366 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
4BBA
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BU of 4bba by Molmil
Crystal structure of glucokinase regulatory protein complexed to phosphate
Descriptor: GLUCOKINASE REGULATORY PROTEIN, PHOSPHATE ION
Authors:Pautsch, A, Stadler, N, Loehle, A, Lenter, M, Rist, W, Berg, A, Glocker, L, Nar, H, Reinhart, D, Heckel, A, Schnapp, G, Kauschke, S.G.
Deposit date:2012-09-21
Release date:2013-05-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal Structure of Glucokinase Regulatory Protein.
Biochemistry, 52, 2013
6Z87
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BU of 6z87 by Molmil
human GTP cyclohydrolase I
Descriptor: GTP cyclohydrolase 1, ZINC ION
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-06-02
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.564 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Z80
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BU of 6z80 by Molmil
stimulatory human GTP cyclohydrolase I - GFRP complex
Descriptor: 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ...
Authors:Ebenhoch, R, Nar, H, Vonck, J.
Deposit date:2020-06-02
Release date:2020-12-09
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Z85
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BU of 6z85 by Molmil
inhibitory human GTP cyclohydrolase I - GFRP complex
Descriptor: 7,8-DIHYDROBIOPTERIN, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ...
Authors:Ebenhoch, R, Nar, H, Vonck, J.
Deposit date:2020-06-02
Release date:2020-12-09
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
7ACC
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BU of 7acc by Molmil
human GTP cyclohydrolase I feedback regulatory protein (GFRP)
Descriptor: GTP cyclohydrolase 1 feedback regulatory protein, POTASSIUM ION
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-09-10
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
7ALA
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BU of 7ala by Molmil
human GCH-GFRP inhibitory complex
Descriptor: 2-azanyl-8-[(4-fluorophenyl)methylsulfanyl]-1,7-dihydropurin-6-one, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ...
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-10-06
Release date:2021-10-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.846 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
7ALC
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BU of 7alc by Molmil
human GCH-GFRP stimulatory complex
Descriptor: GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, PHENYLALANINE, ...
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-10-06
Release date:2021-10-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.726 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
7AL9
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BU of 7al9 by Molmil
human GTP cyclohydrolase I feedback regulatory protein (GFRP) in complex with phenylalanine
Descriptor: GTP cyclohydrolase 1 feedback regulatory protein, PHENYLALANINE, POTASSIUM ION
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-10-06
Release date:2021-10-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.745 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
7ALB
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BU of 7alb by Molmil
human GCH-GFRP stimulatory complex 7-deaza-GTP bound
Descriptor: 7-deaza-GTP, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ...
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-10-06
Release date:2021-10-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.979 Å)
Cite:A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
7ALQ
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BU of 7alq by Molmil
human GCH-GFRP inhibitory complex 7-deaza-GTP bound
Descriptor: 7,8-DIHYDROBIOPTERIN, 7-deaza-GTP, GTP cyclohydrolase 1, ...
Authors:Ebenhoch, R, Nar, H.
Deposit date:2020-10-07
Release date:2021-10-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP.
J.Struct.Biol., 213, 2021

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