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1IRI
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BU of 1iri by Molmil
Crystal structure of human autocrine motility factor complexed with an inhibitor
Descriptor: ERYTHOSE-4-PHOSPHATE, autocrine motility factor
Authors:Tanaka, N, Haga, A, Uemura, H, Akiyama, H, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2001-10-08
Release date:2002-06-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies.
J.Mol.Biol., 318, 2002
1JIQ
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BU of 1jiq by Molmil
Crystal Structure of Human Autocrine Motility Factor
Descriptor: autocrine motility factor
Authors:Tanaka, N, Haga, A, Uemura, H, Akiyama, H, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2001-07-02
Release date:2002-06-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies.
J.Mol.Biol., 318, 2002
4AUO
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BU of 4auo by Molmil
Crystal structure of MMP-1(E200A) in complex with a triple-helical collagen peptide
Descriptor: CALCIUM ION, INTERSTITIAL COLLAGENASE, TRIPLE-HELICAL COLLAGEN PEPTIDE, ...
Authors:Manka, S.W, Carafoli, F, Visse, R, Bihan, D, Raynal, N, Farndale, R.W, Murphy, G, Enghild, J.J, Hohenester, E, Nagase, H.
Deposit date:2012-05-18
Release date:2012-07-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights Into Triple-Helical Collagen Cleavage by Matrix Metalloproteinase 1
Proc.Natl.Acad.Sci.USA, 109, 2012
3WJ4
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BU of 3wj4 by Molmil
Crystal structure of PPARgamma ligand binding domain in complex with tributyltin
Descriptor: Peroxisome proliferator-activated receptor gamma, tributylstannanyl
Authors:Harada, S, Hiromori, Y, Fukakusa, S, Kawahara, K, Nakamura, S, Noda, M, Uchiyama, S, Fukui, K, Nishikawa, J, Nagase, H, Kobayashi, Y, Ohkubo, T, Yoshida, T, Nakanishi, T.
Deposit date:2013-10-04
Release date:2014-10-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds
To be Published
3WJ5
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BU of 3wj5 by Molmil
Crystal structure of PPARgamma ligand binding domain in complex with triphenyltin
Descriptor: Peroxisome proliferator-activated receptor gamma, triphenylstannanyl
Authors:Harada, S, Hiromori, Y, Fukakusa, S, Kawahara, K, Nakamura, S, Noda, M, Uchiyama, S, Fukui, K, Nishikawa, J, Nagase, H, Kobayashi, Y, Ohkubo, T, Yoshida, T, Nakanishi, T.
Deposit date:2013-10-04
Release date:2014-10-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds
To be Published
4FVL
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BU of 4fvl by Molmil
Human collagenase 3 (MMP-13) full form with peptides from pro-domain
Descriptor: CALCIUM ION, CHLORIDE ION, Collagenase 3, ...
Authors:Stura, E.A, Vera, L, Visse, R, Nagase, H, Dive, V.
Deposit date:2012-06-29
Release date:2013-08-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.436 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
4G0D
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BU of 4g0d by Molmil
Human collagenase 3 (MMP-13) full form with peptides from pro-domain
Descriptor: CALCIUM ION, CHLORIDE ION, Collagenase 3, ...
Authors:Stura, E.A, Vera, L, Visse, R, Nagase, H, Dive, V.
Deposit date:2012-07-09
Release date:2013-08-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
4FU4
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BU of 4fu4 by Molmil
Human collagenase 3 (MMP-13) with peptide from pro-domain
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Stura, E.A, Vera, L, Visse, R, Nagase, H, Dive, V.
Deposit date:2012-06-28
Release date:2013-08-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
1UEA
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BU of 1uea by Molmil
MMP-3/TIMP-1 COMPLEX
Descriptor: CALCIUM ION, MATRIX METALLOPROTEINASE-3, TISSUE INHIBITOR OF METALLOPROTEINASE-1, ...
Authors:Bode, W, Maskos, K, Gomis-Rueth, F.-X, Nagase, H.
Deposit date:1997-06-06
Release date:1998-10-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.
Nature, 389, 1997
1SU3
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BU of 1su3 by Molmil
X-ray structure of human proMMP-1: New insights into collagenase action
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Jozic, D, Bourenkov, G, Lim, N.H, Nagase, H, Bode, W, Maskos, K, Structural Proteomics in Europe (SPINE)
Deposit date:2004-03-26
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structure of human proMMP-1: new insights into procollagenase activation and collagen binding.
J.Biol.Chem., 280, 2005
2CXS
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BU of 2cxs by Molmil
Crystal structure of mouse AMF / F6P complex
Descriptor: 6-O-phosphono-beta-D-fructofuranose, GLYCEROL, Glucose-6-phosphate isomerase
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXR
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BU of 2cxr by Molmil
Crystal structure of mouse AMF / 6PG complex
Descriptor: 6-PHOSPHOGLUCONIC ACID, GLYCEROL, Glucose-6-phosphate isomerase
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXT
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BU of 2cxt by Molmil
Crystal structure of mouse AMF / F6P complex
Descriptor: 6-O-phosphono-beta-D-fructofuranose, GLYCEROL, Glucose-6-phosphate isomerase
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXO
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BU of 2cxo by Molmil
Crystal structure of mouse AMF / E4P complex
Descriptor: D-4-PHOSPHOERYTHRONIC ACID, GLYCEROL, Glucose-6-phosphate isomerase
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXU
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BU of 2cxu by Molmil
Crystal structure of mouse AMF / M6P complex
Descriptor: GLYCEROL, Glucose-6-phosphate isomerase, PHOSPHATE ION
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXN
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BU of 2cxn by Molmil
Crystal structure of mouse AMF / phosphate complex
Descriptor: GLYCEROL, Glucose-6-phosphate isomerase, PHOSPHATE ION
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CVP
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BU of 2cvp by Molmil
Crystal structure of mouse AMF
Descriptor: ACETATE ION, GLYCEROL, Glucose-6-phosphate isomerase
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-10
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXQ
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BU of 2cxq by Molmil
Crystal structure of mouse AMF / S6P complex
Descriptor: D-SORBITOL-6-PHOSPHATE, GLYCEROL, Glucose-6-phosphate isomerase
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXP
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BU of 2cxp by Molmil
Crystal structure of mouse AMF / A5P complex
Descriptor: ARABINOSE-5-PHOSPHATE, GLYCEROL, Glucose-6-phosphate isomerase
Authors:Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CLT
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BU of 2clt by Molmil
Crystal structure of the active form (full-length) of human fibroblast collagenase.
Descriptor: CALCIUM ION, INTERSTITIAL COLLAGENASE, ZINC ION
Authors:Iyer, S, Visse, R, Nagase, H, Acharya, K.R.
Deposit date:2006-04-29
Release date:2006-08-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal Structure of an Active Form of Human Mmp-1.
J.Mol.Biol., 362, 2006
3C7X
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BU of 3c7x by Molmil
Hemopexin-like domain of matrix metalloproteinase 14
Descriptor: CHLORIDE ION, Matrix metalloproteinase-14, SODIUM ION
Authors:Tochowicz, A, Itoh, Y, Maskos, K, Bode, W, Goettig, P.
Deposit date:2008-02-08
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions
J.Biol.Chem., 286, 2011
3BA0
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BU of 3ba0 by Molmil
Crystal structure of full-length human MMP-12
Descriptor: ACETOHYDROXAMIC ACID, CALCIUM ION, Macrophage metalloelastase, ...
Authors:Bertini, I, Calderone, V, Fragai, M, Jaiswal, R, Luchinat, C, Melikian, M, Myonas, E, Svergun, D.I.
Deposit date:2007-11-07
Release date:2008-07-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12.
J.Am.Chem.Soc., 130, 2008

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