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2B9E
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BU of 2b9e by Molmil
Human NSUN5 protein
Descriptor: NOL1/NOP2/Sun domain family, member 5 isoform 2, S-ADENOSYLMETHIONINE
Authors:Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-10-11
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Crystal Structure of Human NSUN5 protein in complex with S-adenosyl-L-methionine
To be Published
1PFB
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BU of 1pfb by Molmil
Structural Basis for specific binding of polycomb chromodomain to histone H3 methylated at K27
Descriptor: ACETIC ACID, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Min, J.R, Zhang, Y, Xu, R.-M.
Deposit date:2003-05-24
Release date:2003-10-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27.
Genes Dev., 17, 2003
2QW4
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BU of 2qw4 by Molmil
Human NR4A1 ligand-binding domain
Descriptor: Orphan nuclear receptor NR4A1
Authors:Min, J.R, Schuetz, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2007-08-09
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Nr4A1 Ligand-Binding Domain
To be Published
2AVD
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BU of 2avd by Molmil
Crystal Structure of Human Catechol-O-methyltransferase domain containing 1
Descriptor: Catechol-O-methyltransferase, S-ADENOSYLMETHIONINE
Authors:Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-08-29
Release date:2005-09-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure of Human Catechol-O-methyltransferase domain containing 1 in complex with S-adenosyl-L-methionine
To be Published
2FBM
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BU of 2fbm by Molmil
Acetyltransferase domain of CDY1
Descriptor: CHLORIDE ION, Y chromosome chromodomain protein 1, telomeric isoform b
Authors:Min, J.R, Antoshenko, T, Hong, W, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-12-09
Release date:2005-12-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal Structure of Acetyltransferases domain of Human Testis-specific chromodomain protein Y 1
To be Published
2FW2
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BU of 2fw2 by Molmil
Catalytic domain of CDY
Descriptor: Testis-specific chromodomain protein Y 2
Authors:Min, J.R, Antoshenko, T, Wu, H, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-01-31
Release date:2006-02-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of catalytic domain of Human Testis-specific chromodomain protein Y.
To be Published
2FXF
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BU of 2fxf by Molmil
Human spermidine/spermine N1-acetyltransferase
Descriptor: ACETATE ION, ACETYL COENZYME *A, CALCIUM ION, ...
Authors:Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-02-05
Release date:2006-02-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human spermidine/spermine N1-acetyltransferase
To be Published
2B4Y
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BU of 2b4y by Molmil
Crystal Structure of Human Sirtuin homolog 5
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-5, ...
Authors:Min, J.R, Antoshenko, T, Dong, A, Schuetz, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-09-27
Release date:2006-02-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Human Sirtuin homolog 5 in complex with NAD
To be Published
2F2S
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BU of 2f2s by Molmil
Human mitochondrial acetoacetyl-CoA thiolase
Descriptor: Acetyl-CoA acetyltransferase, mitochondrial, CHLORIDE ION, ...
Authors:Min, J.R, Dombrovski, L, Antoshenko, T, Wu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-11-17
Release date:2005-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human Mitochondrial Acetoacetyl-Coa Thiolase Acat1.
To be Published
2FYT
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BU of 2fyt by Molmil
Human HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae) protein
Descriptor: Protein arginine N-methyltransferase 3, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-02-08
Release date:2006-03-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human HMT1 hnRNP methyltransferase-like 3 in complex with SAH.
To be Published
2GL8
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BU of 2gl8 by Molmil
Human Retinoic acid receptor RXR-gamma ligand-binding domain
Descriptor: Retinoic acid receptor RXR-gamma
Authors:Min, J.R, Schuetz, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-04-04
Release date:2006-04-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of Human Retinoic acid receptor RXR-gamma ligand-binding domain.
To be Published
2H01
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BU of 2h01 by Molmil
PY00414- Plasmodium yoelii thioredoxin peroxidase I
Descriptor: 2-CYS PEROXIREDOXIN
Authors:Artz, J, Qiu, W, Min, J.R, Dong, A, Lew, J, Melone, M, Alam, Z, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
Deposit date:2006-05-12
Release date:2006-05-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of PY00414 - a Plasmodium yoelii thioredoxin peroxidase I
To be Published
1MVX
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BU of 1mvx by Molmil
structure of the SET domain histone lysine methyltransferase Clr4
Descriptor: CRYPTIC LOCI REGULATOR 4, NICKEL (II) ION, SULFATE ION, ...
Authors:Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M.
Deposit date:2002-09-26
Release date:2002-10-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002
1MVH
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BU of 1mvh by Molmil
structure of the SET domain histone lysine methyltransferase Clr4
Descriptor: Cryptic loci regulator 4, NICKEL (II) ION, SULFATE ION, ...
Authors:Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M.
Deposit date:2002-09-25
Release date:2002-10-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002
1NW3
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BU of 1nw3 by Molmil
Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Descriptor: ACETATE ION, S-ADENOSYLMETHIONINE, SULFATE ION, ...
Authors:Min, J.R, Feng, Q, Li, Z.H, Zhang, Y, Xu, R.M.
Deposit date:2003-02-05
Release date:2003-03-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Cell(Cambridge,Mass.), 112, 2003
8K89
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BU of 8k89 by Molmil
Crystal structure of NFIL3
Descriptor: Nuclear factor interleukin-3-regulated protein
Authors:Min, J.R, Chen, S.Z, Liu, K.
Deposit date:2023-07-29
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
J.Biol.Chem., 2024
8K8D
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BU of 8k8d by Molmil
Crystal structure of C/EBPbeta BZIP domain bound to a high affinity DNA
Descriptor: CCAAT/enhancer-binding protein beta, DNA (5'-D(*CP*AP*TP*TP*AP*CP*GP*TP*AP*AP*TP*G)-3')
Authors:Min, J.R, Chen, S.Z, Liu, K.
Deposit date:2023-07-29
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
J.Biol.Chem., 2024
8K8A
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BU of 8k8a by Molmil
Crystal structure of NFIL3 in complex with TTACGTAA DNA
Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*CP*GP*TP*AP*AP*TP*G)-3'), Nuclear factor interleukin-3-regulated protein
Authors:Min, J.R, Chen, S.Z, Liu, K.
Deposit date:2023-07-29
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
J.Biol.Chem., 2024
8K8C
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BU of 8k8c by Molmil
Crystal structure of C/EBPalpha BZIP domain bound to a high affinity DNA
Descriptor: CCAAT/enhancer-binding protein alpha, DNA (5'-D(*CP*AP*TP*TP*AP*CP*GP*TP*AP*AP*TP*GP*A)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*CP*GP*TP*AP*AP*TP*GP*T)-3'), ...
Authors:Min, J.R, Chen, S.Z, Liu, K.
Deposit date:2023-07-29
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
J.Biol.Chem., 2024
8K86
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BU of 8k86 by Molmil
Crystal structure of NFIL3 in complex with TTATGTAA DNA
Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*TP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*AP*CP*AP*TP*AP*AP*TP*G)-3'), Nuclear factor interleukin-3-regulated protein
Authors:Min, J.R, Chen, S.Z, Liu, K.
Deposit date:2023-07-28
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
J.Biol.Chem., 2024
2NYR
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BU of 2nyr by Molmil
Crystal Structure of Human Sirtuin Homolog 5 in Complex with Suramin
Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, NAD-dependent deacetylase sirtuin-5, ZINC ION
Authors:Min, J.R, Antoshenko, T, Allali-Hassani, A, Dong, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-11-21
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin.
Structure, 15, 2007
2O9K
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BU of 2o9k by Molmil
WDR5 in Complex with Dimethylated H3K4 Peptide
Descriptor: H3 HISTONE, WD repeat protein 5
Authors:Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-12-13
Release date:2006-12-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Molecular Recognition and Presentation of Histone H3 by Wdr5.
Embo J., 25, 2006
3C0Y
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BU of 3c0y by Molmil
Crystal structure of catalytic domain of human histone deacetylase HDAC7
Descriptor: Histone deacetylase 7a, POTASSIUM ION, ZINC ION
Authors:Min, J.R, Schuetz, A, Allali-Hassani, A, Loppnau, P, Kwiatkowski, N.P, Mazitschek, R, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2008-01-21
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J.Biol.Chem., 283, 2008
2EX4
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BU of 2ex4 by Molmil
Crystal Structure of Human methyltransferase AD-003 in complex with S-adenosyl-L-homocysteine
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, adrenal gland protein AD-003
Authors:Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-11-07
Release date:2005-11-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Crystal Structure of Human AD-003 protein in complex with S-adenosyl-L-homocysteine
To be Published
2H9L
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BU of 2h9l by Molmil
WDR5delta23
Descriptor: SULFATE ION, WD-repeat protein 5
Authors:Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-06-10
Release date:2006-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006

 

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