Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6H47
DownloadVisualize
BU of 6h47 by Molmil
Human KRAS in complex with darpin K19
Descriptor: GTPase KRas, SULFATE ION, darpin K19
Authors:Debreczeni, J.E, Bery, N, Legg, S, Breed, J, Embrey, K, Stubbs, C, Kolasinska-Zwierz, P, Barrett, N, Marwood, R, Watson, J, Tart, J, Overman, R, Miller, A, Phillips, C, Minter, R, Rabbitts, T.H.
Deposit date:2018-07-20
Release date:2019-04-24
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.
Nat Commun, 10, 2019
6H46
DownloadVisualize
BU of 6h46 by Molmil
Human KRAS in complex with darpin K13
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ...
Authors:Debreczeni, J.E, Bery, N, Legg, S, Breed, J, Embrey, K, Stubbs, C, Kolasinska-Zwierz, P, Barrett, N, Marwood, R, Watson, J, Tart, J, Overman, R, Miller, A, Phillips, C, Minter, R, Rabbitts, T.H.
Deposit date:2018-07-20
Release date:2019-04-24
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.
Nat Commun, 10, 2019
5UHY
DownloadVisualize
BU of 5uhy by Molmil
A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
Descriptor: ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein
Authors:Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G.
Deposit date:2017-01-12
Release date:2017-03-29
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
1LVQ
DownloadVisualize
BU of 1lvq by Molmil
IC3 of CB1 Bound to G(alpha)i
Descriptor: Cannabinoid receptor 1
Authors:Ulfers, A.L, McMurry, J.L, Miller, A, Wang, L, Kendall, D.A, Mierke, D.F.
Deposit date:2002-05-29
Release date:2002-12-11
Last modified:2012-07-25
Method:SOLUTION NMR
Cite:Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity.
Protein Sci., 11, 2002
1LVR
DownloadVisualize
BU of 1lvr by Molmil
IC3 of CB1 (L431A,A432L) Bound to G(alpha)i
Descriptor: Cannabinoid receptor 1
Authors:Ulfers, A.L, McMurry, J.L, Miller, A, Wang, L, Kendall, D.A, Mierke, D.F.
Deposit date:2002-05-29
Release date:2002-12-11
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity.
Protein Sci., 11, 2002
1BOY
DownloadVisualize
BU of 1boy by Molmil
EXTRACELLULAR REGION OF HUMAN TISSUE FACTOR
Descriptor: HUMAN TISSUE FACTOR
Authors:Boys, C.W.G, Tuddenham, E.G.D, Harlos, K.
Deposit date:1996-01-11
Release date:1996-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the extracellular region of human tissue factor.
Nature, 370, 1994
5N88
DownloadVisualize
BU of 5n88 by Molmil
Crystal structure of antibody bound to viral protein
Descriptor: PC4 and SFRS1-interacting protein, VH59 antibody
Authors:Bao, L, Hannon, C, Cruz-Migoni, A, Ptchelkine, D, Sun, M.-y, Derveni, M, Bunjobpol, W, Chambers, J.S, Simmons, A, Phillips, S.E.V, Rabbitts, T.H.
Deposit date:2017-02-23
Release date:2017-12-20
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein.
Sci Rep, 7, 2017
6W09
DownloadVisualize
BU of 6w09 by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, E3, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-02-29
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6W1C
DownloadVisualize
BU of 6w1c by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-03-04
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6VYV
DownloadVisualize
BU of 6vyv by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-02-27
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.33 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6W2U
DownloadVisualize
BU of 6w2u by Molmil
Mayaro Virus glycoprotein E1 ectodomain and glycoportien E2 ectodomain asymmetric unit
Descriptor: Spike glycoprotein E1, Spike glycoprotein E2
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-03-08
Release date:2020-10-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
7QI0
DownloadVisualize
BU of 7qi0 by Molmil
Crystal structure of KLK6 in complex with compound DKFZ918
Descriptor: (5~{R})-3-(6-carbamimidoylpyridin-3-yl)-~{N}-[(1~{S})-1-naphthalen-1-ylpropyl]-2-oxidanylidene-1,3-oxazolidine-5-carboxamide, Kallikrein-6
Authors:Jagtap, P.K.A, Baumann, A, Lohbeck, J, Isak, D, Miller, A, Hennig, J.
Deposit date:2021-12-14
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Scalable synthesis and structural characterization of reversible KLK6 inhibitors.
Rsc Adv, 12, 2022
7QHZ
DownloadVisualize
BU of 7qhz by Molmil
Crystal structure of KLK6 in complex with compound DKFZ917
Descriptor: (5~{R})-3-(4-carbamimidoylphenyl)-~{N}-[(1~{S})-1-naphthalen-1-ylpropyl]-2-oxidanylidene-1,3-oxazolidine-5-carboxamide, GLYCEROL, Kallikrein-6
Authors:Jagtap, P.K.A, Baumann, A, Lohbeck, J, Isak, D, Miller, A, Hennig, J.
Deposit date:2021-12-14
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Scalable synthesis and structural characterization of reversible KLK6 inhibitors.
Rsc Adv, 12, 2022
6GOE
DownloadVisualize
BU of 6goe by Molmil
KRAS full length G12V GPPNHP
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Ehebauer, M.T, Phillips, S.V.E, Rabbitts, T.H.
Deposit date:2018-06-01
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GOG
DownloadVisualize
BU of 6gog by Molmil
KRAS-169 Q61H GPPNHP
Descriptor: CITRIC ACID, GTPase KRas, MAGNESIUM ION, ...
Authors:Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Phillips, S.V.E, Rabbitts, T.H.
Deposit date:2018-06-01
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GOF
DownloadVisualize
BU of 6gof by Molmil
KRAS full length G12D GPPNHP
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Ehebauer, M.T, Phillips, S.V.E, Rabbitts, T.H.
Deposit date:2018-06-01
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GQW
DownloadVisualize
BU of 6gqw by Molmil
KRAS-169 Q61H GPPNHP + CH-1
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Phillips, S.E.V, Rabbitts, T.H.
Deposit date:2018-06-08
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GQY
DownloadVisualize
BU of 6gqy by Molmil
KRAS-169 Q61H GPPNHP + CH-3
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Phillips, S.V.E, Rabbitts, T.H.
Deposit date:2018-06-08
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GQT
DownloadVisualize
BU of 6gqt by Molmil
KRAS-169 Q61H GPPNHP + PPIN-2
Descriptor: CITRIC ACID, GTPase KRas, MAGNESIUM ION, ...
Authors:Cruz-Migoni, A, Canning, P, Quevedo, C.E, Carr, S.B, Phillips, S.E.V, Rabbitts, T.H.
Deposit date:2018-06-08
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GOD
DownloadVisualize
BU of 6god by Molmil
KRAS full length wild-type GPPNHP
Descriptor: GLYCEROL, GTPase KRas, MAGNESIUM ION, ...
Authors:Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Ehebauer, M.T, Phillips, S.V.E, Rabbitts, T.H.
Deposit date:2018-06-01
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GQX
DownloadVisualize
BU of 6gqx by Molmil
KRAS-169 Q61H GPPNHP + CH-2
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Phillips, S.E.V, Rabbitts, T.H.
Deposit date:2018-06-08
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GOM
DownloadVisualize
BU of 6gom by Molmil
KRAS-169 Q61H GPPNHP + PPIN-1
Descriptor: (6~{S})-1-(1~{H}-imidazol-4-ylcarbonyl)-6-[(4-phenylphenyl)methyl]-4-propyl-1,4-diazepan-5-one, CITRIC ACID, GTPase KRas, ...
Authors:Cruz-Migoni, A, Canning, P, Quevedo, C.E, Carr, S.B, Phillips, S.E.V, Rabbitts, T.H.
Deposit date:2018-06-01
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6F76
DownloadVisualize
BU of 6f76 by Molmil
Antibody derived (Abd-8) small molecule binding to KRAS.
Descriptor: 4-(2,3-dihydro-1,4-benzodioxin-5-yl)-~{N}-[3-[(dimethylamino)methyl]phenyl]-2-methoxy-aniline, GTPase KRas, MAGNESIUM ION, ...
Authors:Bery, N, Cruz-Migoni, A, Quevedo, C.E, Phillips, S.V.E, Carr, S, Rabbitts, T.H.
Deposit date:2017-12-07
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions.
Elife, 7, 2018
8BAX
DownloadVisualize
BU of 8bax by Molmil
X-ray structure of the CeuE Homologue from Geobacillus stearothermophilus - azotochelin complex.
Descriptor: Azotochelin, FE (III) ION, Siderophore ABC transporter substrate-binding protein
Authors:Blagova, E.V, Miller, A, Dodson, E.J, Booth, R, Duhme-Klair, A.K, Wilson, K.S.
Deposit date:2022-10-12
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Thermostable homologues of the periplasmic siderophore-binding protein CeuE from Geobacillus stearothermophilus and Parageobacillus thermoglucosidasius.
Acta Crystallogr D Struct Biol, 79, 2023
8BAW
DownloadVisualize
BU of 8baw by Molmil
X-ray structure of the CeuE Homologue from Geobacillus stearothermophilus - 5-LICAM siderophore analogue complex.
Descriptor: FE (III) ION, N,N'-pentane-1,5-diylbis(2,3-dihydroxybenzamide), Siderophore ABC transporter substrate-binding protein
Authors:Blagova, E.V, Miller, A, Booth, R, Dodson, E.J, Duhme-Klair, A.K, Wilson, K.S.
Deposit date:2022-10-12
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.471 Å)
Cite:Thermostable homologues of the periplasmic siderophore-binding protein CeuE from Geobacillus stearothermophilus and Parageobacillus thermoglucosidasius.
Acta Crystallogr D Struct Biol, 79, 2023

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon