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2O8Z
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BU of 2o8z by Molmil
Bound Structure of CRF1 Extracellular Domain Antagonist
Descriptor: cCRF(30-41) Peptide
Authors:Mesleh, M.F, Shirley, W.A, Heise, C.E, Ling, N, Maki, R.A, Laura, R.P.
Deposit date:2006-12-12
Release date:2006-12-26
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR structural characterization of a minimal peptide antagonist bound to the extracellular domain of the corticotropin-releasing factor1 receptor.
J.Biol.Chem., 282, 2007
1WAZ
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BU of 1waz by Molmil
NMR Structure Determination of the bacterial mercury transporter, MerF, in micelles
Descriptor: MERF
Authors:Howell, S.C, Mesleh, M.F, Opella, S.J.
Deposit date:2004-10-28
Release date:2005-04-11
Last modified:2019-04-03
Method:SOLUTION NMR
Cite:NMR Structure Determination of a Membrane Protein with Two Transmembrane Helices in Micelles: Merf of the Bacterial Mercury Detoxification System
Biochemistry, 44, 2005
1NH4
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BU of 1nh4 by Molmil
Structure of the coat protein in fd filamentous bacteriophage particles
Descriptor: Major coat protein
Authors:Zeri, A.C, Mesleh, M.F, Nevzorov, A.A, Opella, S.J.
Deposit date:2002-12-18
Release date:2003-05-06
Last modified:2022-02-23
Method:SOLID-STATE NMR
Cite:Structure of the coat protein in fd filamentous bacteriophage particles determined by solid-state NMR spectroscopy
Proc.Natl.Acad.Sci.USA, 100, 2003
1PI7
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BU of 1pi7 by Molmil
Structure of the channel-forming trans-membrane domain of Virus protein "u" (Vpu) from HIV-1
Descriptor: VPU protein
Authors:Park, S.H, Mrse, A.A, Nevzorov, A.A, Mesleh, M.F, Oblatt-Montal, M, Montal, M, Opella, S.J.
Deposit date:2003-05-29
Release date:2003-11-11
Last modified:2021-10-27
Method:SOLID-STATE NMR
Cite:Three-dimensional structure of the channel-forming trans-membrane domain of virus protein "u" (Vpu) from HIV-1
J.Mol.Biol., 333, 2003
1PI8
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BU of 1pi8 by Molmil
Structure of the channel-forming trans-membrane domain of Virus protein "u" (Vpu) from HIV-1
Descriptor: VPU protein
Authors:Park, S.H, Mrse, A.A, Nevzorov, A.A, Mesleh, M.F, Oblatt-Montal, M, Montal, M, Opella, S.J.
Deposit date:2003-05-29
Release date:2003-11-11
Last modified:2021-10-27
Method:SOLID-STATE NMR
Cite:Three-dimensional structure of the channel-forming trans-membrane domain of virus protein "u" (Vpu) from HIV-1
J.Mol.Biol., 333, 2003
1PJE
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BU of 1pje by Molmil
Structure of the channel-forming trans-membrane domain of Virus protein "u"(Vpu) from HIV-1
Descriptor: VPU protein
Authors:Park, S.H, Mrse, A.A, Nevzorov, A.A, Mesleh, M.F, Oblatt-Montal, M, Montal, M, Opella, S.J.
Deposit date:2003-06-02
Release date:2003-10-14
Last modified:2021-10-27
Method:SOLID-STATE NMR
Cite:Three-dimensional structure of the channel-forming trans-membrane domain of Virus protein "u" (Vpu) from HIV-1
J.Mol.Biol., 333, 2003
5CTX
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BU of 5ctx by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-phenyl-3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, DNA gyrase subunit B, ...
Authors:Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
Deposit date:2015-07-24
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
5CPH
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BU of 5cph by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
Descriptor: (3E)-3-(pyridin-3-ylmethylidene)-1,3-dihydro-2H-indol-2-one, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit B, ...
Authors:Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
Deposit date:2015-07-21
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
5CTW
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BU of 5ctw by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(butanoylamino)thiophene-3-carboxamide, CHLORIDE ION, ...
Authors:Andersen, O.A, Barker, J, Hadfield, A.T, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
Deposit date:2015-07-24
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
5CTU
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BU of 5ctu by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(thiophen-2-yl)thieno[2,3-d]pyrimidin-4(1H)-one, CHLORIDE ION, ...
Authors:Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
Deposit date:2015-07-24
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
5CTY
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BU of 5cty by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, CHLORIDE ION, ...
Authors:Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D.
Deposit date:2015-07-24
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
2C0X
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BU of 2c0x by Molmil
MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION AND SOLID-STATE NMR DATA
Descriptor: COAT PROTEIN B
Authors:Marvin, D.A, Welsh, L.C, Symmons, M.F, Scott, W.R.P, Straus, S.K.
Deposit date:2005-09-08
Release date:2005-12-14
Last modified:2020-07-29
Method:SOLID-STATE NMR
Cite:Molecular Structure of Fd (F1, M13) Filamentous Bacteriophage Refined with Respect to X-Ray Fibre Diffraction and Solid-State NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane.
J.Mol.Biol., 355, 2006
6V0P
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BU of 6v0p by Molmil
PRMT5 complex bound to covalent PBM inhibitor BRD6711
Descriptor: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-sulfamoylphenyl)acetamide, CHLORIDE ION, GLYCEROL, ...
Authors:McMillan, B.J, McKinney, D.C.
Deposit date:2019-11-19
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021
7M05
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BU of 7m05 by Molmil
CryoEM structure of PRMT5 bound to covalent PBM-site inhibitor BRD-6988
Descriptor: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-{[2-(pyridin-2-yl)ethyl]sulfamoyl}phenyl)acetamide, Methylosome protein 50, Protein arginine N-methyltransferase 5
Authors:McMillan, B.J, McKinney, D.C, Timm, D.E.
Deposit date:2021-03-10
Release date:2021-03-17
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021

217705

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