Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3SN6
DownloadVisualize
BU of 3sn6 by Molmil
Crystal structure of the beta2 adrenergic receptor-Gs protein complex
Descriptor: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Camelid antibody VHH fragment, Endolysin,Beta-2 adrenergic receptor, ...
Authors:Rasmussen, S.G.F, DeVree, B.T, Zou, Y, Kruse, A.C, Chung, K.Y, Kobilka, T.S, Thian, F.S, Chae, P.S, Pardon, E, Calinski, D, Mathiesen, J.M, Shah, S.T.A, Lyons, J.A, Caffrey, M, Gellman, S.H, Steyaert, J, Skiniotis, G, Weis, W.I, Sunahara, R.K, Kobilka, B.K.
Deposit date:2011-06-28
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the beta2 adrenergic receptor-Gs protein complex
Nature, 477, 2011
6WPW
DownloadVisualize
BU of 6wpw by Molmil
GCGR-Gs signaling complex bound to a designed glucagon derivative
Descriptor: Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Hilger, D, Krishna Kumar, K, Hu, H, Mathiesen, J.M, Skiniotis, G, Kobilka, B.K.
Deposit date:2020-04-28
Release date:2020-08-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into differences in G protein activation by family A and family B GPCRs.
Science, 369, 2020
6N4X
DownloadVisualize
BU of 6n4x by Molmil
Metabotropic Glutamate Receptor 5 Apo Form Ligand Binding Domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Metabotropic glutamate receptor 5
Authors:Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K.
Deposit date:2018-11-20
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566, 2019
6N50
DownloadVisualize
BU of 6n50 by Molmil
Metabotropic Glutamate Receptor 5 Extracellular Domain in Complex with Nb43 and L-quisqualic acid
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ...
Authors:Koehl, A, Hu, H, Feng, D, Sun, B, Chu, M, Weis, W.I, Skiniotis, G, Mathiesen, J.M, Kobilka, B.K.
Deposit date:2018-11-20
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.751 Å)
Cite:Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566, 2019
6N4Y
DownloadVisualize
BU of 6n4y by Molmil
Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ...
Authors:Koehl, A, Hu, H, Feng, D, Sun, B, Chu, M, Weis, W.I, Mathiesen, J.M, Skiniotis, G, Kobilka, B.K.
Deposit date:2018-11-20
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.262 Å)
Cite:Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566, 2019
6N52
DownloadVisualize
BU of 6n52 by Molmil
Metabotropic Glutamate Receptor 5 Apo Form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5
Authors:Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K.
Deposit date:2018-11-20
Release date:2019-01-23
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566, 2019
6N51
DownloadVisualize
BU of 6n51 by Molmil
Metabotropic Glutamate Receptor 5 bound to L-quisqualate and Nb43
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ...
Authors:Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K.
Deposit date:2018-11-20
Release date:2019-01-23
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566, 2019
4DKL
DownloadVisualize
BU of 4dkl by Molmil
Crystal structure of the mu-opioid receptor bound to a morphinan antagonist
Descriptor: CHLORIDE ION, CHOLESTEROL, Mu-type opioid receptor, ...
Authors:Manglik, A, Kruse, A.C, Kobilka, T.S, Thian, F.S, Mathiesen, J.M, Sunahara, R.K, Pardo, L, Weis, W.I, Kobilka, B.K, Granier, S.
Deposit date:2012-02-03
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the {mu}-opioid receptor bound to a morphinan antagonist.
Nature, 485, 2012
6E67
DownloadVisualize
BU of 6e67 by Molmil
Structure of beta2 adrenergic receptor fused to a Gs peptide
Descriptor: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Beta-2 adrenergic receptor,Endolysin,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Beta-2 adrenergic receptor chimera
Authors:Liu, X, Xu, X, Hilger, D, Tiemann, J, Liu, H, Du, Y, Hirata, K, Sun, X, Guixa-Gonzalez, R, Mathiesen, J, Hildebrand, P, Kobilka, B.
Deposit date:2018-07-24
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural Insights into the Process of GPCR-G Protein Complex Formation.
Cell, 177, 2019
6W2Y
DownloadVisualize
BU of 6w2y by Molmil
CryoEM Structure of GABAB1b Homodimer
Descriptor: (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Papasergi-Scott, M.M, Robertson, M.J, Skiniotis, G.
Deposit date:2020-03-08
Release date:2020-07-01
Last modified:2020-08-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of metabotropic GABABreceptor.
Nature, 584, 2020
8FU6
DownloadVisualize
BU of 8fu6 by Molmil
GCGR-Gs complex in the presence of RAMP2
Descriptor: Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Krishna Kumar, K, O'Brien, E.S, Wang, H, Montabana, E, Kobilka, B.K.
Deposit date:2023-01-16
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Negative allosteric modulation of the glucagon receptor by RAMP2.
Cell, 186, 2023
6W2X
DownloadVisualize
BU of 6w2x by Molmil
CryoEM Structure of Inactive GABAB Heterodimer
Descriptor: (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Papasergi-Scott, M.M, Robertson, M.J, Skiniotis, G.
Deposit date:2020-03-08
Release date:2020-07-01
Last modified:2020-08-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of metabotropic GABABreceptor.
Nature, 584, 2020
6EG8
DownloadVisualize
BU of 6eg8 by Molmil
Structure of the GDP-bound Gs heterotrimer
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Hilger, D, Liu, X, Aschauer, P, Kobilka, B.K.
Deposit date:2018-08-19
Release date:2019-06-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Process of GPCR-G Protein Complex Formation.
Cell, 177, 2019
8SZI
DownloadVisualize
BU of 8szi by Molmil
Cryo-EM structure of PAM-free human calcium-sensing receptor CaSR-Gi complex in lipid nanodiscs
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:He, F, Wu, C, Gao, Y, Skiniotis, G.
Deposit date:2023-05-29
Release date:2024-02-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
8SZG
DownloadVisualize
BU of 8szg by Molmil
Cryo-EM structure of cinacalcet-bound human calcium-sensing receptor CaSR-Gq complex in lipid nanodiscs
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:He, F, Wu, C, Gao, Y, Skiniotis, G.
Deposit date:2023-05-29
Release date:2024-02-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
8SZF
DownloadVisualize
BU of 8szf by Molmil
Cryo-EM structure of cinacalcet-bound active-state human calcium-sensing receptor CaSR in lipid nanodiscs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:He, F, Wu, C, Gao, Y, Skiniotis, G.
Deposit date:2023-05-29
Release date:2024-02-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
8SZH
DownloadVisualize
BU of 8szh by Molmil
Cryo-EM structure of cinacalcet-bound human calcium-sensing receptor CaSR-Gi complex in lipid nanodiscs
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:He, F, Wu, C, Gao, Y, Skiniotis, G.
Deposit date:2023-05-29
Release date:2024-02-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
7M3G
DownloadVisualize
BU of 7m3g by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3J
DownloadVisualize
BU of 7m3j by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3E
DownloadVisualize
BU of 7m3e by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7M3F
DownloadVisualize
BU of 7m3f by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
7MTQ
DownloadVisualize
BU of 7mtq by Molmil
CryoEM Structure of Full-Length mGlu2 in Inactive-State Bound to Antagonist LY341495
Descriptor: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2
Authors:Seven, A.B, Barros-Alvarez, X, Skiniotis, G.
Deposit date:2021-05-13
Release date:2021-07-07
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:G-protein activation by a metabotropic glutamate receptor.
Nature, 595, 2021
7MTR
DownloadVisualize
BU of 7mtr by Molmil
CryoEM Structure of Full-Length mGlu2 Bound to Ago-PAM ADX55164 and Glutamate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine, GLUTAMIC ACID, ...
Authors:Seven, A.B, Barros-Alvarez, X, Skiniotis, G.
Deposit date:2021-05-13
Release date:2021-07-07
Last modified:2021-09-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:G-protein activation by a metabotropic glutamate receptor.
Nature, 595, 2021
7MTS
DownloadVisualize
BU of 7mts by Molmil
CryoEM Structure of mGlu2 - Gi Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine, GLUTAMIC ACID, ...
Authors:Seven, A.B, Barros-Alvarez, X, Skiniotis, G.
Deposit date:2021-05-13
Release date:2021-07-07
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:G-protein activation by a metabotropic glutamate receptor.
Nature, 595, 2021

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon