6K60
 
 | | Structural and functional basis for HLA-G isoform recognition of immune checkpoint receptor LILRBs | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain G, ... | | Authors: | Kuroki, K, Matsubara, H, Kanda, R, Miyashita, N, Shiroishi, M, Fukunaga, Y, Kamishikiryo, J, Fukunaga, A, Hirose, K, Sugita, Y, Kita, S, Ose, T, Maenaka, K. | | Deposit date: | 2019-05-31 | | Release date: | 2019-11-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.149 Å) | | Cite: | Structural and Functional Basis for LILRB Immune Checkpoint Receptor Recognition of HLA-G Isoforms.
J Immunol., 203, 2019
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3WV0
 | | O-glycan attached to herpes simplex virus type 1 glycoprotein gB is recognized by the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha | | Descriptor: | Envelope glycoprotein B, N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2-deoxy-alpha-D-galactopyranose, Paired immunoglobulin-like type 2 receptor alpha, ... | | Authors: | Kuroki, K, Wang, J, Ose, T, Yamaguchi, M, Tabata, S, Maita, N, Nakamura, S, Kajikawa, M, Kogure, A, Satoh, T, Arase, H, Maenaka, K. | | Deposit date: | 2014-05-10 | | Release date: | 2014-06-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILR alpha
Proc.Natl.Acad.Sci.USA, 111, 2014
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3WUZ
 | | Crystal structure of the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha | | Descriptor: | CITRIC ACID, ISOPROPYL ALCOHOL, Paired immunoglobulin-like type 2 receptor alpha | | Authors: | Kuroki, K, Wang, J, Ose, T, Yamaguchi, M, Tabata, S, Maita, N, Nakamura, S, Kajikawa, M, Kogure, A, Satoh, T, Arase, H, Maenaka, K. | | Deposit date: | 2014-05-10 | | Release date: | 2014-06-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILR alpha
Proc.Natl.Acad.Sci.USA, 111, 2014
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1UGN
 | | Crystal structure of LIR1.02, one of the alleles of LIR1 | | Descriptor: | Leukocyte immunoglobulin-like receptor 1 | | Authors: | Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K. | | Deposit date: | 2003-06-17 | | Release date: | 2004-08-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis.
Hum.Mol.Genet., 14, 2005
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4WCO
 | | Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A | | Descriptor: | ACETATE ION, C-type lectin domain family 2 member D, SULFATE ION, ... | | Authors: | Kita, S, Matsubara, H, Kasai, Y, Tamaoki, T, Okabe, Y, Fukuhara, H, Kamishikiryo, J, Ose, T, Kuroki, K, Maenaka, K. | | Deposit date: | 2014-09-05 | | Release date: | 2015-06-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A
Eur.J.Immunol., 45, 2015
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2UWM
 | | C-TERMINAL DOMAIN(WH2-WH4) OF ELONGATION FACTOR SELB IN COMPLEX WITH SECIS RNA | | Descriptor: | 5'-R(*GP*GP*CP*GP*UP*UP*GP*CP*CP*GP *GP*UP*CP*UP*GP*GP*CP*AP*AP*CP*GP*CP*C)-3', SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR | | Authors: | Ose, T, Soler, N, Rasubala, L, Kuroki, K, Kohda, D, Fourmy, D, Yoshizawa, S, Maenaka, K. | | Deposit date: | 2007-03-22 | | Release date: | 2007-05-08 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Structural Basis for Dynamic Interdomain Movement and RNA Recognition of the Selenocysteine-Specific Elongation Factor Selb.
Structure, 15, 2007
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8IAY
 | | Crystal structure of canine distemper virus hemagglutinin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein | | Authors: | Fukuhara, H, Yumoto, K, Sako, M, Kajikawa, M, Ose, T, Hashiguchi, T, Kamishikiryo, J, Maita, N, Kuroki, K, Maenaka, K. | | Deposit date: | 2023-02-09 | | Release date: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.027 Å) | | Cite: | Glycan-shielded homodimer structure and dynamical features of the canine distemper virus hemagglutinin relevant for viral entry and efficient vaccination
Elife, 2024
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5XOF
 | | Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide I | | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Nitric oxide synthase, ... | | Authors: | Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, H, Anada, M, Ose, T, Hashimoto, S, Maenaka, K. | | Deposit date: | 2017-05-28 | | Release date: | 2017-10-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.963 Å) | | Cite: | Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor.
J. Biol. Chem., 292, 2017
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5XO2
 | | Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide II | | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2,4-dideoxy-alpha-D-xylo-hexopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Envelope glycoprotein B | | Authors: | Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, S, Anada, M, Ose, T, Hashimoto, S, Maenaka, K. | | Deposit date: | 2017-05-25 | | Release date: | 2017-10-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor.
J. Biol. Chem., 292, 2017
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6K6N
 | | Crystal structure of SIVmac239 Nef protein | | Descriptor: | Protein Nef | | Authors: | Hirao, K, Andrews, S, Kuroki, K, Kusaka, H, Tadokoro, T, Kita, S, Ose, T, Rowland-Jones, S, Maenaka, K. | | Deposit date: | 2019-06-04 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.0002 Å) | | Cite: | Structure of HIV-2 Nef Reveals Features Distinct from HIV-1 Involved in Immune Regulation.
Iscience, 23, 2020
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6K6M
 | | Crystal structure of HIV-2 Nef protein | | Descriptor: | Protein Nef | | Authors: | Hirao, K, Andrews, S, Kuroki, K, Kusaka, H, Tadokoro, T, Kita, S, Ose, T, Rowland-Jones, S, Maenaka, K. | | Deposit date: | 2019-06-04 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.072 Å) | | Cite: | Structure of HIV-2 Nef Reveals Features Distinct from HIV-1 Involved in Immune Regulation.
Iscience, 23, 2020
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6IMF
 | | Crystal structure of TOXIN/ANTITOXIN complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cysteine-rich venom protein triflin, GLYCEROL, ... | | Authors: | Shioi, N, Tadokoro, T, Shioi, S, Hu, Y, Kurahara, L.H, Okabe, Y, Matsubara, H, Kita, S, Ose, T, Kuroki, K, Maenaka, K, Terada, S. | | Deposit date: | 2018-10-22 | | Release date: | 2018-12-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the complex between venom toxin and serum inhibitor from Viperidae snake.
J. Biol. Chem., 294, 2019
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1VDG
 | | Crystal structure of LIR1.01, one of the alleles of LIR1 | | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 1 | | Authors: | Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K. | | Deposit date: | 2004-03-22 | | Release date: | 2005-08-02 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of LIR1.03, one of the alleles of LIR1
To be Published
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2ZB6
 | | Crystal structure of the measles virus hemagglutinin (oligo-sugar type) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin protein | | Authors: | Hashiguchi, T, Kajikawa, M, Maita, N, Takeda, M, Kuroki, K, Sasaki, K, Kohda, D, Yanagi, Y, Maenaka, K. | | Deposit date: | 2007-10-16 | | Release date: | 2007-11-06 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of measles virus hemagglutinin provides insight into effective vaccines
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ZB5
 | | Crystal structure of the measles virus hemagglutinin (complex-sugar-type) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin protein | | Authors: | Hashiguchi, T, Kajikawa, M, Maita, N, Takeda, M, Kuroki, K, Sasaki, K, Kohda, D, Yanagi, Y, Maenaka, K. | | Deposit date: | 2007-10-16 | | Release date: | 2007-11-06 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of measles virus hemagglutinin provides insight into effective vaccines
Proc.Natl.Acad.Sci.Usa, 104, 2007
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3A3Q
 | | Structure of N59D HEN EGG-WHITE LYSOZYME in complex with (GlcNAc)3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C | | Authors: | Ose, T, Kuroki, K, Matsushima, M, Maenaka, K, Kumagai, I. | | Deposit date: | 2009-06-16 | | Release date: | 2009-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Importance of the hydrogen bonding network including Asp52 for catalysis, as revealed by Asn59 mutant hen egg-white lysozymes
J.Biochem., 146, 2009
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3A3R
 | | Structure of N59D HEN EGG-WHITE LYSOZYME | | Descriptor: | Lysozyme C | | Authors: | Ose, T, Kuroki, K, Matsushima, M, Maenaka, K, Kumagai, I. | | Deposit date: | 2009-06-16 | | Release date: | 2009-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Importance of the hydrogen bonding network including Asp52 for catalysis, as revealed by Asn59 mutant hen egg-white lysozymes
J.Biochem., 146, 2009
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2DYP
 | | Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G | | Descriptor: | 9 Mer Peptide From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Shiroishi, M, Kuroki, K, Rasubala, L, Kohda, D, Maenaka, K. | | Deposit date: | 2006-09-15 | | Release date: | 2006-11-07 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2D31
 | | Crystal structure of disulfide-linked HLA-G dimer | | Descriptor: | 9-mer peptide from Histone H2A, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Shiroishi, M, Kuroki, K, Ose, T, Rasubala, L, Shiratori, I, Arase, H, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K. | | Deposit date: | 2005-09-23 | | Release date: | 2006-03-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Efficient Leukocyte Ig-like Receptor Signaling and Crystal Structure of Disulfide-linked HLA-G Dimer
J.Biol.Chem., 281, 2006
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2D3V
 | | Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11) | | Descriptor: | leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 1 | | Authors: | Shiroishi, M, Kajikawa, M, Kuroki, K, Ose, T, Kohda, D, Maenaka, K. | | Deposit date: | 2005-10-03 | | Release date: | 2006-06-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of the human monocyte-activating receptor,
J.Biol.Chem., 281, 2006
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3W39
 | | Crystal structure of HLA-B*5201 in complexed with HIV immunodominant epitope (TAFTIPSI) | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-52 alpha chain, ... | | Authors: | Yagita, Y, Kuse, N, Kuroki, K, Gatanaga, H, Carlson, J.M, Chikata, T, Brumme, Z.L, Murakoshi, H, Akahoshi, T, Pfeifer, N, Mallal, S, John, M, Ose, T, Matsubara, H, Kanda, R, Fukunaga, Y, Honda, K, Kawashima, Y, Ariumi, Y, Oka, S, Maenaka, K, Takiguchi, M. | | Deposit date: | 2012-12-13 | | Release date: | 2013-02-13 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity
J.Virol., 87, 2013
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3WMD
 | | Crystal structure of epoxide hydrolase MonBI | | Descriptor: | Probable monensin biosynthesis isomerase | | Authors: | Minami, A, Ose, T, Sato, K, Oikawa, A, Kuroki, K, Maenaka, K, Oguri, H, Oikawa, H. | | Deposit date: | 2013-11-16 | | Release date: | 2014-01-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.999 Å) | | Cite: | Allosteric regulation of epoxide opening cascades by a pair of epoxide hydrolases in monensin biosynthesis
Acs Chem.Biol., 9, 2014
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