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4GW1
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BU of 4gw1 by Molmil
cQFD Meditope
Descriptor: Fab heavy chain, Fab light chain, PHOSPHATE ION, ...
Authors:Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C.
Deposit date:2012-08-31
Release date:2013-10-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GW5
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BU of 4gw5 by Molmil
cQYN meditope - Cetuximab Fab
Descriptor: Fab Heavy Chain, Fab Light Chain, PHOSPHATE ION, ...
Authors:Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C.
Deposit date:2012-08-31
Release date:2013-10-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HJG
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BU of 4hjg by Molmil
Meditope-enabled trastuzumab
Descriptor: Immunoglobulin G-binding protein A, Protein L fragment, Trastuzumab heavy chain, ...
Authors:Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C.
Deposit date:2012-10-12
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
5TBW
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BU of 5tbw by Molmil
Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D.
Deposit date:2016-09-13
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
5HPM
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BU of 5hpm by Molmil
Cetuximab Fab in complex with cyclic linked meditope
Descriptor: 2-AMINO-3-MERCAPTO-PROPIONAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-01-20
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5HYQ
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BU of 5hyq by Molmil
Cetuximab Fab in complex with amidated meditope
Descriptor: Amidated meditope, Cetuximab heavy chain, Cetuximab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-01
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.477 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5I2I
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BU of 5i2i by Molmil
Structure of cetuximab Fab with cyclic F3Q variant of the meditope
Descriptor: Cetuximab Fab heavy chain, Cetuximab Fab light chain, Meditope, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-08
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICX
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BU of 5icx by Molmil
Cetuximab Fab in complex with CQFDLSTRRLRCGGSK meditope
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ID1
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BU of 5id1 by Molmil
Cetuximab Fab in complex with MPT-Cys meditope
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IR1
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BU of 5ir1 by Molmil
Cetuximab Fab in complex with 3-bromophenylalanine meditope variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-11
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.482 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ID0
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BU of 5id0 by Molmil
Cetuximab Fab in complex with aminoheptanoic acid-linked meditope
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICY
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BU of 5icy by Molmil
Cetuximab Fab in complex with linear meditope
Descriptor: Cetuximab Fab heavy chain, Cetuximab Fab light chain, Meditope, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IOP
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BU of 5iop by Molmil
Cetuximab Fab in complex with 4-bromophenylalanine meditope variant
Descriptor: Cetuximab Fab, heavy chain, light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-08
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICZ
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BU of 5icz by Molmil
Cetuximab Fab in complex with GQFDLSTRRLKG peptide
Descriptor: Cetuximab Fab heavy chain, Cetuximab Fab light chain, Meditope, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IV2
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BU of 5iv2 by Molmil
Cetuximab Fab in complex with Arg9Cir meditope variant
Descriptor: Cetuximab Fab, heavy chain, light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-18
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.481 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IVZ
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BU of 5ivz by Molmil
Cetuximab Fab in complex with Arg8Cir meditope variant
Descriptor: Cetuximab Fab, heavy chain, light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-21
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ITF
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BU of 5itf by Molmil
Cetuximab Fab in complex with 2-bromophenylalanine meditope variant
Descriptor: Cetuximab Fab, heavy chain, light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-16
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
6AU5
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BU of 6au5 by Molmil
Structure of cetuximab with aminoheptanoic acid-linked n-butylarginine meditope variant
Descriptor: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-08-30
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6AYN
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BU of 6ayn by Molmil
Structure of cetuximab with aminoheptanoic acid-linked N-(3-aminopropyl)-L-arginine meditope variant
Descriptor: Cetuximab Fab heavy chain, Cetuximab Fab light chain, Cyclic meditope
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-09-08
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6AZK
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BU of 6azk by Molmil
Structure of cetuximab with aminoheptanoic acid-linked N-(3-hydroxypropyl)-L-arginine meditope variant
Descriptor: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-09-11
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.477 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6AXP
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BU of 6axp by Molmil
Structure of cetuximab with aminoheptanoic acid-linked n-octylarginine meditope variant
Descriptor: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-09-07
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6BAH
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BU of 6bah by Molmil
Trastuzumab Fab v3 with 5-diphenyl meditope variant
Descriptor: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain,IGH@ protein, ...
Authors:Bzymek, K.P, King, J.D, Williams, J.C.
Deposit date:2017-10-12
Release date:2018-09-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
6AZL
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BU of 6azl by Molmil
Structure of cetuximab with aminoheptanoic acid-linked N-carboxyethylarginine meditope variant
Descriptor: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-09-11
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.482 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6BAE
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BU of 6bae by Molmil
Trastuzumab Fab v3 in complex with CQFDLSTRRLKC
Descriptor: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ...
Authors:Bzymek, K.P, King, J.D, Williams, J.C.
Deposit date:2017-10-12
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
6B9Y
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BU of 6b9y by Molmil
Trastuzumab Fab v3 in complex with 5-phenyl meditope variant
Descriptor: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ...
Authors:Bzymek, K.P, King, J.D, Williams, J.C.
Deposit date:2017-10-11
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018

 

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