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6DCX
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BU of 6dcx by Molmil
iASPP-PP-1c structure and targeting of p53
Descriptor: RelA-associated inhibitor, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Authors:Glover, J.N.M, Zhou, Y, Edwards, R.A.
Deposit date:2018-05-08
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.408 Å)
Cite:Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis.
Structure, 27, 2019
5U6K
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BU of 5u6k by Molmil
Crystal structure of TopBP1 BRCT4/5 in complex with a BLM phosphopeptide
Descriptor: Bloom Sydrome recQ helicase like protein (BLM), DNA topoisomerase 2-binding protein 1
Authors:Glover, J.N.M, Sun, L, Edwards, R.A.
Deposit date:2016-12-08
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insight into BLM Recognition by TopBP1.
Structure, 25, 2017
7RGU
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BU of 7rgu by Molmil
The crystal structure of RocC bound to a transcriptional terminator
Descriptor: Modified SL3 of RocR, Repressor of competence, RNA Chaperone
Authors:Kim, H.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2022-11-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.
Nat Commun, 13, 2022
7RGS
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BU of 7rgs by Molmil
The crystal structure of RocC, containing FinO domain, 24-126
Descriptor: Repressor of competence, RNA Chaperone
Authors:Kim, H.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.
Nat Commun, 13, 2022
7RGT
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BU of 7rgt by Molmil
The crystal structure of RocC, containing FinO domain, 1-126
Descriptor: Repressor of competence, RNA Chaperone, SULFATE ION
Authors:Kim, H.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2022-11-30
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.
Nat Commun, 13, 2022
8D34
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BU of 8d34 by Molmil
Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
Descriptor: Uridylate-specific endoribonuclease nsp15
Authors:Farraj, R.A, Edwards, R.A, Glover, J.N.M.
Deposit date:2022-05-31
Release date:2023-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
To Be Published
1N5O
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BU of 1n5o by Molmil
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Williams, R.S, Glover, J.N.M.
Deposit date:2002-11-06
Release date:2002-12-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
J.Biol.Chem., 278, 2003
2F9D
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BU of 2f9d by Molmil
2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of SF3b155
Descriptor: Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, Edwards, R.A, Ritchie, D.B, Glover, J.N.M, Macmillan, A.M.
Deposit date:2005-12-05
Release date:2006-01-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a core spliceosomal protein interface
Proc.Natl.Acad.Sci.Usa, 103, 2006
1T2V
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BU of 1t2v by Molmil
Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide
Descriptor: BRCTide-7PS, Breast cancer type 1 susceptibility protein
Authors:Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M.
Deposit date:2004-04-22
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1T2U
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BU of 1t2u by Molmil
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M.
Deposit date:2004-04-22
Release date:2004-05-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1MN4
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BU of 1mn4 by Molmil
Structure of Ndt80 (Residues 59-340) DNA-binding domain core
Descriptor: NDT80 PROTEIN
Authors:Lamoureux, J.S, Stuart, D, Tsang, R, Wu, C, Glover, J.N.M.
Deposit date:2002-09-04
Release date:2002-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
4KQD
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BU of 4kqd by Molmil
The crystal Structure of the N-terminal PAS domain of the F plasmid TraJ
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DITHIANE DIOL, GLYCEROL, ...
Authors:Lu, J, Glover, J.N.M.
Deposit date:2013-05-14
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The crystal Structure of the N-terminal PAS domain of the F plasmid TraJ
To be Published
3D8A
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BU of 3d8a by Molmil
Co-crystal structure of TraM-TraD complex.
Descriptor: Protein traD, Relaxosome protein TraM
Authors:Glover, J.N.M, Lu, J, Wong, J.J, Edwards, R.A.
Deposit date:2008-05-22
Release date:2008-09-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of specific TraD-TraM recognition during F plasmid-mediated bacterial conjugation.
Mol.Microbiol., 70, 2008
1FOS
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BU of 1fos by Molmil
TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES
Descriptor: C-JUN PROTO-ONCOGENE PROTEIN, DNA (5'-D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP*T)-3'), ...
Authors:Glover, J.N.M, Harrison, S.C.
Deposit date:1995-03-07
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.
Nature, 373, 1995
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
Descriptor: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-09-23
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (8.3 Å)
Cite:RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016
4QPO
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BU of 4qpo by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Descriptor: PHOSPHATE ION, Relaxosome protein TraM
Authors:Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
Deposit date:2014-06-24
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
4QPQ
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BU of 4qpq by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Descriptor: Relaxosome protein TraM, sbmA DNA1, sbmA DNA2
Authors:Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
Deposit date:2014-06-24
Release date:2014-09-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
2RH3
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BU of 2rh3 by Molmil
Crystal structure of plasmid pTiC58 VirC2
Descriptor: Protein virC2
Authors:Lu, J, Glover, J.N.M.
Deposit date:2007-10-05
Release date:2008-10-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Agrobacterium tumefaciens VirC2 enhances T-DNA transfer and virulence through its C-terminal ribbon-helix-helix DNA-binding fold
Proc.Natl.Acad.Sci.USA, 106, 2009
1DVO
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BU of 1dvo by Molmil
THE X-RAY CRYSTAL STRUCTURE OF FINO, A REPRESSOR OF BACTERIAL CONJUGATION
Descriptor: FERTILITY INHIBITION PROTEIN O
Authors:Ghetu, A.F, Gubbins, M.J, Frost, L.S, Glover, J.N.M.
Deposit date:2000-01-21
Release date:2000-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the bacterial conjugation repressor finO.
Nat.Struct.Biol., 7, 2000
3JVE
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BU of 3jve by Molmil
Crystal Structure of the Sixth BRCT Domain of TopBP1
Descriptor: DNA topoisomerase 2-binding protein 1
Authors:Leung, C.C, Kellogg, E, Baker, D, Glover, J.N.M.
Deposit date:2009-09-16
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1.
Protein Sci., 19, 2010
1A02
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BU of 1a02 by Molmil
STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
Descriptor: AP-1 FRAGMENT FOS, AP-1 FRAGMENT JUN, DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), ...
Authors:Chen, L, Glover, J.N.M, Hogan, P.G, Rao, A, Harrison, S.C.
Deposit date:1997-12-08
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.
Nature, 392, 1998
2F9J
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BU of 2f9j by Molmil
3.0 angstrom resolution structure of a Y22M mutant of the spliceosomal protein p14 bound to a region of SF3b155
Descriptor: Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, MacMillan, A.M.
Deposit date:2005-12-06
Release date:2006-01-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a core spliceosomal protein interface
Proc.Natl.Acad.Sci.Usa, 103, 2006
3U7G
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BU of 3u7g by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7E
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BU of 3u7e by Molmil
Crystal structure of mPNKP catalytic fragment (D170A)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, GLYCEROL, MAGNESIUM ION, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7F
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BU of 3u7f by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011

 

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