4GXB
 
 | | Structure of the SNX17 atypical FERM domain bound to the NPxY motif of P-selectin | | Descriptor: | GLYCEROL, P-selectin, Sorting nexin-17 | | Authors: | Ghai, R, Bugarcic, A, Liu, H, Norwood, S.J, Li, S.S, Teasdale, R.D, Collins, B.M. | | Deposit date: | 2012-09-04 | | Release date: | 2013-03-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
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5U78
 | | Crystal structure of ORP8 PH domain in P1211 space group | | Descriptor: | Oxysterol-binding protein-related protein 8 | | Authors: | Ghai, R, Yang, H. | | Deposit date: | 2016-12-12 | | Release date: | 2017-10-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.978 Å) | | Cite: | ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.
Nat Commun, 8, 2017
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5U77
 | | Crystal structure of ORP8 PH domain | | Descriptor: | FORMIC ACID, N-(2-hydroxyethyl)-N,N-dimethyl-3-sulfopropan-1-aminium, Oxysterol-binding protein-related protein 8 | | Authors: | Ghai, R, Yang, H. | | Deposit date: | 2016-12-11 | | Release date: | 2017-10-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.157 Å) | | Cite: | ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.
Nat Commun, 8, 2017
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3LUI
 | | Crystal structure of the SNX17 PX domain with bound sulphate | | Descriptor: | SULFATE ION, Sorting nexin-17 | | Authors: | Ghai, R, Collins, B.M. | | Deposit date: | 2010-02-17 | | Release date: | 2010-03-02 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases
Proc.Natl.Acad.Sci.USA, 2011
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6BP6
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8F2U
 | | Human CCC complex | | Descriptor: | COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ... | | Authors: | Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J. | | Deposit date: | 2022-11-08 | | Release date: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
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8F2R
 | | Human CCC complex | | Descriptor: | COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ... | | Authors: | Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J. | | Deposit date: | 2022-11-08 | | Release date: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
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4P2A
 | | Structure of mouse VPS26A bound to rat SNX27 PDZ domain | | Descriptor: | MERCURY (II) ION, Sorting nexin-27, Vacuolar protein sorting-associated protein 26A | | Authors: | Clairfeuille, T, Gallon, M, Mas, C, Ghai, R, Teasdale, R, Cullen, P, Collins, B. | | Deposit date: | 2014-03-03 | | Release date: | 2014-09-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3PSN
 | | Crystal structure of mouse VPS29 complexed with Mn2+ | | Descriptor: | MANGANESE (II) ION, Vacuolar protein sorting-associated protein 29 | | Authors: | Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B. | | Deposit date: | 2010-12-02 | | Release date: | 2010-12-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
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3PSO
 | | Crystal structure of mouse VPS29 complexed with Zn2+ | | Descriptor: | Vacuolar protein sorting-associated protein 29, ZINC ION | | Authors: | Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B. | | Deposit date: | 2010-12-02 | | Release date: | 2010-12-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
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8R8D
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7RM8
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8ESD
 | | Crystal structure of COMMD7-COMMD9-COMMD5-COMMD10 tetramer | | Descriptor: | COMM domain-containing protein 10, COMM domain-containing protein 5, COMM domain-containing protein 7, ... | | Authors: | Healy, M.D, Collins, B.M. | | Deposit date: | 2022-10-13 | | Release date: | 2023-05-24 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
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8ESE
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6EYU
 | | Crystal structure of the inward H(+) pump xenorhodopsin | | Descriptor: | Bacteriorhodopsin, EICOSANE, RETINAL, ... | | Authors: | Kovalev, K, Shevchenko, V, Polovinkin, V, Mager, T, Gushchin, I, Melnikov, I, Borshchevskiy, V, Popov, A, Alekseev, A, Gordeliy, V. | | Deposit date: | 2017-11-13 | | Release date: | 2017-12-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Inward H(+) pump xenorhodopsin: Mechanism and alternative optogenetic approach.
Sci Adv, 3, 2017
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4PQP
 | | Crystal structure of human SNX14 PX domain in space group P43212 | | Descriptor: | GLYCEROL, Sorting nexin-14 | | Authors: | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | | Deposit date: | 2014-03-03 | | Release date: | 2014-09-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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4PQO
 | | Structure of the human SNX14 PX domain in space group I41 | | Descriptor: | Sorting nexin-14 | | Authors: | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | | Deposit date: | 2014-03-03 | | Release date: | 2014-09-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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4NKN
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4OE9
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6XS7
 | | Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D2 | | Descriptor: | 48V-DTY-THR-THR-ILE-TYR-TRP-THR-PRO-LEU-GLY-THR-PHE-PRO-ARG-ILE-ARG, FORMIC ACID, GLYCEROL, ... | | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | | Deposit date: | 2020-07-15 | | Release date: | 2021-07-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
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6XSA
 | | Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L2 | | Descriptor: | 48V-TYR-LEU-PRO-THR-ILE-THR-GLY-VAL-GLY-HIS-LEU-TRP-HIS-PRO-LEU, SULFATE ION, Vacuolar protein sorting-associated protein 29 | | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | | Deposit date: | 2020-07-15 | | Release date: | 2021-07-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
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6XS5
 | | Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D1 | | Descriptor: | 48V-DTY-ILE-ILE-ASP-THR-PRO-LEU-GLY-VAL-PHE-LEU-SER-SER-LEU-LYS-ARG, FORMIC ACID, GLYCEROL, ... | | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | | Deposit date: | 2020-07-15 | | Release date: | 2021-07-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
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6XS9
 | | Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L1 | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 48V-TYR-ILE-LYS-THR-PRO-LEU-GLY-THR-PHE-PRO-ASN-ARG-HIS-GLY, GLYCEROL, ... | | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | | Deposit date: | 2020-07-15 | | Release date: | 2021-07-21 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
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6XS8
 | | Crystal structure of Chaetomium thermophilum Vps29 complexed with RaPID-derived cyclic peptide RT-D3 | | Descriptor: | 48V-DTY-GLY-TYR-ASP-PRO-LEU-GLY-LEU-LYS-TYR-PHE-ALA, Vacuolar protein sorting-associated protein 29 | | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | | Deposit date: | 2020-07-15 | | Release date: | 2021-07-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.95009851 Å) | | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
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4P2I
 | | Crystal structure of the mouse SNX19 PX domain | | Descriptor: | MKIAA0254 protein | | Authors: | Collins, B.M. | | Deposit date: | 2014-03-04 | | Release date: | 2014-09-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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