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1TTV
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BU of 1ttv by Molmil
NMR Structure of a Complex Between MDM2 and a Small Molecule Inhibitor
Descriptor: 1-{[4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]CARBONYL}PIPERAZINE, Ubiquitin-protein ligase E3 Mdm2
Authors:Fry, D.C, Emerson, S.D, Palme, S, Vu, B.T, Liu, C.M, Podlaski, F.
Deposit date:2004-06-23
Release date:2005-01-04
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:NMR structure of a complex between MDM2 and a small molecule inhibitor.
J.Biomol.Nmr, 30, 2004
1RFA
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BU of 1rfa by Molmil
NMR SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF C-RAF-1
Descriptor: RAF1
Authors:Emerson, S.D, Madison, V.S, Palermo, R.E, Waugh, D.S, Scheffler, J.E, Tsao, K.-L, Kiefer, S.E, Liu, S.P, Fry, D.C.
Deposit date:1995-04-26
Release date:1996-06-20
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the Ras-binding domain of c-Raf-1 and identification of its Ras interaction surface.
Biochemistry, 34, 1995
4J7D
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BU of 4j7d by Molmil
The 1.25A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5045331
Descriptor: (4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole, E3 ubiquitin-protein ligase Mdm2, SULFATE ION
Authors:Janson, C, Lukacs, C, Graves, B.
Deposit date:2013-02-13
Release date:2013-08-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Deconstruction of a nutlin: dissecting the binding determinants of a potent protein-protein interaction inhibitor.
ACS Med Chem Lett, 4, 2013
4J74
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BU of 4j74 by Molmil
The 1.2A crystal structure of humanized Xenopus MDM2 with RO0503918 - a nutlin fragment
Descriptor: (4S,5R)-4,5-bis(4-chlorophenyl)-2-methyl-4,5-dihydro-1H-imidazole, E3 ubiquitin-protein ligase Mdm2, SULFATE ION
Authors:Janson, C, Lukacs, C, Kammlott, U, Graves, B.
Deposit date:2013-02-12
Release date:2013-08-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Deconstruction of a nutlin: dissecting the binding determinants of a potent protein-protein interaction inhibitor.
ACS Med Chem Lett, 4, 2013
4J7E
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BU of 4j7e by Molmil
The 1.63A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5524529
Descriptor: E3 ubiquitin-protein ligase Mdm2, SULFATE ION, [(4S,5R)-4,5-bis(4-chlorophenyl)-2,4,5-trimethyl-4,5-dihydro-1H-imidazol-1-yl]{4-[3-(methylsulfonyl)propyl]piperazin-1-yl}methanone
Authors:Janson, C, Lukacs, C, Graves, B.
Deposit date:2013-02-13
Release date:2013-08-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Deconstruction of a nutlin: dissecting the binding determinants of a potent protein-protein interaction inhibitor.
ACS Med Chem Lett, 4, 2013

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